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A Case of Localized Skin Infection Due to Scedosporium apiospermum Diagnosed by DNA Sequencing of the Internal Transcribed Spacer Region
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À¯Áö¿µ(Yoo Ji-Young) - µ¿±¹´ëÇб³ ÀÇ°ú´ëÇÐ ÇǺΰúÇб³½Ç
¼ÛÀ¯¹ü(Song You-Bum) - µ¿±¹´ëÇб³ ÀÇ°ú´ëÇÐ ÇǺΰúÇб³½Ç
¼¹«±Ô(Suh Moo-Kyu) - µ¿±¹´ëÇб³ ÀÇ°ú´ëÇÐ ÇǺΰúÇб³½Ç
ÇÏ°æÀÓ(Ha Gyoung-Yim) - µ¿±¹´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
ÀÌÁ¾ÀÓ(Lee Jong-Im) - µ¿±¹´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç
¼Û½ÂÇö(Sohng Seung-Hyun) - ¿µ³²´ëÇб³ ÀÇ°ú´ëÇÐ ÇǺΰúÇб³½Ç
Abstract
Scedosporium apiospermum is an asexual state of Pseudallescheria boydii which has been isolated from soil, sewage, and decaying vegetation. It can cause cutaneous infections by traumatic implantation of the contaminant due to penetrating injury. This ubiquitous fungus cause not only mycetoma, but also infections of variety of body sites including the skin. The localized skin infection due to this organism is much rare than mycetoma. We report a case of cutaneous S. apiospermum infection occurred in 80-year-old male. The skin lesion was manifested by a 8.0 ¡¿ 4.0 cm-sized erythematous plaque with pustules and crusts on the dorsum of right hand. The fungal culture from the biopsy specimen on Sabouraud¡¯s dextrose agar showed white to gray colored cottony colonies of S. apiospermum. The nucleotide sequence of internal transcribed spacer for clinical isolate was identical to that of S. apiospermum strain IHEM 23829. The patient was treated with oral fluconazole for 3 months.
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Localized skin infection, Scedosporium apiospermum
KMID :
0670820140190020045
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