Clinical Characteristics of the Development of Pneumothorax in Mechanically Ventilated Patients in Intensive Care Units

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±è¿Ïö(Kim Wan-Chul) - Gyeongsang National University School of Medicine Department of Internal Medicine
ÀÓ¼öÁø(Lim Su-Jin) - Gyeongsang National University School of Medicine Department of Internal Medicine
±è°æ¿µ(Kim Kyong-Young) - Gyeongsang National University School of Medicine Department of Internal Medicine
À̽ÂÁØ(Lee Seung-Jun) - Gyeongsang National University School of Medicine Department of Internal Medicine
Á¶À¯Áö(Cho Yu-Ji) - Gyeongsang National University School of Medicine Department of Internal Medicine
Á¤ÀÌ¿µ(Jeong Yi-Yeong) - Gyeongsang National University School of Medicine Department of Internal Medicine
¹Ú¹ÌÁ¤(Park Mi-Jung) - Gyeongsang National University School of Medicine Departments of Diagnostic Radiology
(Jeon Kyoung-Nyeo) - Gyeongsang National University School of Medicine Departments of Diagnostic Radiology
ÀÌÁ¾´ö(Lee Jong-Deog) - Gyeongsang National University School of Medicine Department of Internal Medicine
Ȳ¿µ½Ç(Hwang Young-Sil) - Gyeongsang National University School of Medicine Department of Internal Medicine
±èȣö(Kim Ho-Cheol) - Gyeongsang National University School of Medicine Department of Internal Medicine

Abstract

Background: Pneumothorax (PTX) can occur as a complication of positive pressure ventilation in mechanically ventilated patients.

Methods: We retrospectively reviewed the clinical characteristics of patients who developed PTX during mechanical ventilation (MV) in the intensive care unit (ICU).

Results: Of the 326 patients admitted (208 men and 118 women; mean age, 65.3 ¡¾ 8.74 years), 15 (4.7%) developed PTX, which was MV-associated in 11 (3.3%) cases (6 men and 5 women; mean age, 68.3 ¡¾ 9.12 years) and procedure-associated in 4. Among the patients with MV-associated PTX, the underlying lung diseases were acute respiratory distress syndrome in 7 patients, interstitial lung disease in 2 patients, and chronic obstructive pulmonary disease in 2 patients. PTX diagnosis was achieved by chest radiography alone in 9 patients and chest computed tomography alone in 2 patients. Nine patients were using assist-control mode MV with the mean applied positive end-expiratory pressure, 9 ¡¾ 4.6 cmH2O and the mean tidal volume, 361 ¡¾ 63.7 ml at the diagnosis of PTX. Two patients died as a result of MV-associated PTX and their systolic pressure was below 80 mmHg and heart rates were less than 80/min. Ten patients were treated by chest tube insertion, and 1 patient was treated by percutaneous pigtail catheter insertion.

Conclusions: PTX can develop in patients undergoing MV, and may cause death. Early recognition and treatment are necessary to prevent hemodynamic compromise in patients who develop PTX.

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intensive care unit, mechanical ventilation, pneumothorax
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