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Efficacy and Tolerability of Valproic Acid Once Daily Dosing for Juvenile Myoclonic Epilepsy
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À¯¼±¿µ(Yoo Sun-Young) - ÀüºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¼Ò¾Æ°úÇб³½Ç
À̹Î(Lee Min) - ÀüºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¼Ò¾Æ°úÇб³½Ç
±è¼øÃ¶(Kim Soon-Chul) - ÀüºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¼Ò¾Æ°úÇб³½Ç
±è¼±ÁØ(Kim Sun-Jun) - ÀüºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¼Ò¾Æ°úÇб³½Ç
Abstract
¸ñÀû: º» ¿¬±¸´Â ÈĵνŰæÅëÀ¸·Î Áø´ÜµÈ ¼Ò¾ÆÃ»¼Ò³âµé¿¡°Ô ÈĵνŰæÂ÷´Ü¼úÀ» ½ÃÇàÇßÀ»¶§ÀÇ È¿°ú¿Í ¾ÈÀü¼º¿¡ ´ëÇØ ¾Ë¾Æº¸¾Ò´Ù.
¹æ¹ý: 2005³â 7¿ùºÎÅÍ 2013³â 7¿ù±îÁö ÀüºÏ´ëÇб³ ¾î¸°À̺´¿ø ¼Ò¾ÆÃ»¼Ò³â°ú¿¡ ³»¿øÇÏ¿´´ø 5-19¼¼ÀÇ ÈĵνŰæÅë ȯÀÚ 47¸íÀ» ´ë»óÀ¸·Î ÈĵνŰæÂ÷´Ü¼úÀ» ½ÃÇàÇϰí ÀüÈÄÀÇ ½Ã°¢ÅëÁõôµµ ºñ±³, ºÎÀÛ¿ë ¿©ºÎµîÀ» È®ÀÎÇÏ¿© ÈĵνŰæÂ÷´Ü¼úÀÇ À¯¿ë¼º°ú ¾ÈÀü¼º¿¡ ´ëÇØ Á¶»çÇÏ¿´´Ù.
°á°ú: ÃÑ 47¸í Áß ÈĵνŰæÅëÀ¸·Î¸¸ Áø´ÜµÈ °æ¿ì 25¸í(53.2%), ÆíµÎÅëÀÌ µ¿¹ÝµÈ °æ¿ì 13¸í(27.7%), ±äÀ强 µÎÅëÀÌ µ¿¹ÝµÈ °æ¿ì 8¸í(17.0%), ½Å»ý ÀÏ»ó¼º Áö¼Ó¼º µÎÅëÀÌ µ¿¹ÝµÈ °æ¿ì 1¸í(2.1%)À̾ú´Ù. ÈĵνŰæÂ÷´Ü¼ú ÈÄ 25¸í(53.2%)¿¡¼ µÎÅëÀÌ Àç¹ßÇÏ¿´°í, Àç¹ßÇϱâ±îÁöÀÇ ±â°£ÀÌ °¡Àå ±æ¾ú´ø °æ¿ì´Â 4°³¿ùÀ̾ú°í Àç¹ßÇÏ´Â °æ¿ì Æò±Õ 4-5ÁÖ Á¤µµ ÈÄ¿¡ Àç¹ßÇÏ¿´´Ù. ±×·¯³ª µÎÅëÀÌ Àç¹ßµÇ¾ú¾îµµ ¾à¹°Ä¡·á ¾øÀÌ µÎÅëÀÌ È£ÀüµÇ¾ú´ø °æ¿ì´Â 14¸í(56.0%) ÀÌ¿´´Ù. ÈĵνŰæÅë¿¡ ´ëÇÑ Ä¡·á´Â ÈĵνŰæÂ÷´Ü¼ú 47(100%)¿¡ ÀÇÇØ ÀÌ·ç¾îÁ³À¸¸ç, ½Ã¼úÀü°ú ½Ã¼ú ÈÄÀÇ ÅëÁõ Á¤µµ¸¦ ºñ±³ÇÑ °á°ú 41¸í(87.2%)¿¡¼ ½Ã¼ú ÈÄ ÅëÁõ Á¤µµ°¡ °¨¼ÒÇÏ¿´°í, 6¸í(12.8%)Àº ÅëÁõ Á¤µµ¿¡ º¯È°¡ ¾ø¾ú´Ù. Æò±Õ 4.7ÀÇ ÅëÁõôµµ °¨¼Ò¸¦ º¸¿´´Ù. ÈĵνŰæÂ÷´Ü¼ú ÈÄ ÁÖ»çºÎÀ§ÀÇ ÀϽÃÀûÀÎ ÅëÁõÀ» º¸ÀÎ °æ¿ì¸¦ Á¦¿ÜÇϰí´Â Ưº°ÇÑ ºÎÀÛ¿ëÀº ¾ø¾ú´Ù.
°á·Ð: ÈĵνŰæÅëÀ» Áø´Ü¹ÞÀº ¼Ò¾ÆÃ»¼Ò³âµé¿¡°Ô ÈĵνŰæÂ÷´Ü¼úÀ» ½ÃÇàÇÏ´Â °ÍÀº ¾ÈÀüÇϰí È¿°úÀûÀÎ Ä¡·á¹ýÀ̸ç, µû¶ó¼ ¸¸¼º, ³Ä¡¼º µÎÅë ȯÀڵ鿡°Ô ÈĵνŰæÅëÀÌ µ¿¹ÝµÇ¾î ÀÖ´ÂÁö À¯¹«¸¦ È®ÀÎÇϰí, ÈĵνŰæÅë¿¡ È¿°úÀûÀÎ ÈĵνŰæÂ÷´Ü¼úÀ» Ä¡·á¹ýÀ¸·Î Á¶±â¿¡ ½ÃÇàÇÏ´Â °ÍÀÌ ÇÊ¿äÇÏ´Ù.
Purpose: The aim of the this study was to verify the efficacy of the occipital nerve block (ONB) for occipital neuralgia pediatric patients who has tender point around suboccipital area.
Methods: In a retro¡¯spective way, 47 pediatric patients with occipital neuralgia were enrolled during July 2005 to July 2013. Diagnosis of occipital neuralgia is made by the International headache society criteria (2004, 2nd edition). We conducted a chart review of all the ONB performed in our clinic over 9 years. Patients were analyzed according to gender, headache type, headache duration and frequency, family history, medication history before ONB, symptoms with headache, recurrence, complications, magnetic resonance imaging scan and electroencephalogram results. Headache was measured before and after the procedure using the visual analog pain indexes.
Results: Forty seven (100%) patients were treated with occipital nerve block. Pain indexes were declined in 41 (87.2%) patients, but 6 (12.8%) were not response. Mean visual analog pain index scores declined by 4.7 units. Twenty five (53.2%) patients experienced recurrence of the disorder, but 14 (56.0%) patients were relived without the need for any further treatment. No complications were reported.
Conclusion: Our data suggests that occipital nerve block was safe and effective treatment for the children with occipital neuralgia.
Ű¿öµå
Neuralgia, Nerve block, Child
KMID :
0391520140220020077
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