5년간 모든 수혈 환자를 대상으로 시행한 Dia를 포함한 Type and Screen법과 Immediate Spin Crossmatch 적용
Applied the “Type and Screen” Method Based on Antibody Screening Test Including Dia Cells and Immediate Spin Crossmatch to All Patients Who Received Transfusion for Five Years

대한수혈학회지 2013년 24권 3호 p.258 ~ p.264

김혜림(Kim Hye-Rim) - 부산대학교 의과대학 진단검사의학교실
김형회(Kim Hyung-Hoi) - 부산대학교 의과대학 진단검사의학교실

Abstract

Background: To prevent a hemolytic transfusion reaction caused by an unexpected antibody, a crossmatch following ABO/Rh typing and antibody screening test is performed before a red cell transfusion. The conventional crossmatch method is usually performed using the room temperature saline method, 37oC albumin method, and anti-globulin method. With growth and development of techniques for laboratory and records management, demand for reduction of work load is on the rise, therefore, use of the “type and screen” method and Immediate spin crossmatch as a pretransfusion test is recommended.

Methods: A retrospective analysis was performed using records from the Pusan National University Hospital blood bank from 2008 to 2012. Room temperature saline method omitting the anti-globulin crossmatch has been used in order to issue a compatible red cell product, when antibody screening performed using a cell panel (DiaCell I-II-Dia) in all patients where a request for a red cell transfusion was sent to the blood bank is negative, without previously identified unexpected antibodies.

Results: In total, 107,569 units of PRBCs were requested, 100,978 units (93.88%) were issued only immediate-spin crossmatch following type and screen method, and exclusion criteria were indicated in 6.12% of the total. There was no single case where the antibody screen was negative with guarantee of compatibility and hemolytic transfusion reaction occurred.

Conclusion: The “Type and Screen” method based on antibody screening test including Dia cells and Immediate spin crossmatch application can contribute to safe, efficient transfusion service in the blood bank.

키워드

Type and screen method, Antibody screening, Transfusion, Cross-matching
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학술진흥재단(KCI) KoreaMed 대한의학회 회원 
주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
The “Type and Screen” method based on antibody screening test including Dia cells and Immediate spin crossmatch application can contribute to safe, efficient transfusion service in the blood bank.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
KCD코드
ICD 03
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