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Detection of Anti-Lua in an Unexpected Antibody Screening Test: A Case Report and Literature Review
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¼Û»õ¾Ï(Song Sae-Am) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
¿À½Âȯ(Oh Seung-Hwan) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
¹Úżº(Park Tae-Sung) - °æÈñ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø Áø´Ü°Ë»çÀÇÇб³½Ç
¼ÕÇý¼ö(Son Hye-Soo) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
¼º¼º°æ(Sung Sung-Kyung) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
ÀÌÀÚ¿µ(Lee Ja-Young) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
Àü°æ¶õ(Jun Kyung-Ran) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
½ÅÁ¤È¯(Shin Jeong-Hwan) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
±èÇý¶õ(Kim Hye-Ran) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
ÀÌÁ¤³à(Lee Jeong-Nyeo) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü°Ë»çÀÇÇб³½Ç
Abstract
Lutheran a antigen (Lua) is detected in 6 to 8% of Caucasians and Africans. In Korean and other Asian populations, it is very rare or nearly absent. Therefore, although Lua has a considerable immunizing capacity, sensitization to Lua is a rare event. Here we report on a rare case of anti-Lua in a 70 year-old female patient with Lu (a?/b£«) phenotype and review the relevant literature. Due to the paucity of Lua positive panel cells in antibody screening and identification tests, detection of this rare antibody to Lua antigen is not feasible. Therefore, we should keep in mind the possibility of the misleading false negative result in detection of antibody to this low incidence antigen.
Å°¿öµå
Lutheran blood group system, Anti-Lua alloantibody, Antibody screening test
KMID :
0387720120230020169
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À¯È¿¼º°á°ú(Recomendation)
Due to the paucity of Lua positive panel cells in antibody screening and identification tests, detection of this ra.re antibody to Lua antigen is not feasible.