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의료시설폐렴(Healthcare-associated pneumonia) 환자의 중증도 예측에 있어 프로칼시토닌 농도 측정의 유용성
Usefulness of Procalcitonin Levels in Assessing Severity in Patients with Healthcare-associated Pneumonia

대한응급의학회지 2014년 25권 3호 p.299 ~ p.306

박종호(Park Jong-Ho) - 건국대학교 의학전문대학원 응급의학교실
김종원(Kim Jong-Won) - 건국대학교 의학전문대학원 응급의학교실
박상민(Park Sang-Min) - 건국대학교 의학전문대학원 응급의학교실
이경룡(Lee Kyeong-Ryong) - 건국대학교 의학전문대학원 응급의학교실
박상오(Park Sang-O) - 건국대학교 의학전문대학원 응급의학교실
백광제(Baek Kwang-Je) - 건국대학교 의학전문대학원 응급의학교실
홍대영(Hong Dae-Young) - 건국대학교 의학전문대학원 응급의학교실

Abstract

Purpose: Healthcare-associated pneumonia (HCAP) has been proposed as a new category of pneumonia. However, studies of HCAP patients in Korea are limited. The aim of this study was to investigate the usefulness of procalcitonin (PCT) in assessment of the severity of HCAP patients.

Methods: We conducted a retrospective study of patients with HCAP who were hospitalized between August 2009 and July 2013. We evaluated white blood cell, C-reactive protein, and PCT, along with the pneumonia severity index score and CURB-65 in HCAP patients.

Results: The mean age of the 78 patients was 77.5 years. The PSI and CURB-65 scores showed similar trends of increasing mortality with worsening risk class in HCAP patients. The median PCT level was significantly higher in the non-survival group than in the survival group (3.1 ng/mL vs 0.4 ng/mL, p=0.003). The PCT level was significantly higher in patients with positive blood cultures (0.95 ng/mL vs 0.36 ng/mL, p=0.010). PCT levels rose consistently asPSI class advanced from class I/II/III to class V (p<0.001).In receiver operating characteristic curves analysis for prediction of mortality, PCT level had an area under the curve (AUC) of 0.655 (95% confidence interval 0.523-0.786).

Conclusion: We found that measurement of PCT in the emergency department may provide helpful information for use in assessment of HCAP patients.

키워드

Pneumonia, Severity of illness index, Procalcitonin

KMID : 0385920140250030299

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주제코드

주제명(Target field)

연구대상(Population)

연구참여(Sample size)

대상성별(Gender)

질병특성(Condition Category)

연구환경(Setting)

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DOI

KCD코드

ICD 03

건강보험코드

의료시설폐렴(Healthcare-associated pneumonia) 환자의 중증도 예측에 있어 프로칼시토닌 농도 측정의 유용성 Usefulness of Procalcitonin Levels in Assessing Severity in Patients with Healthcare-associated Pneumonia

Abstract

키워드

의료시설폐렴(Healthcare-associated pneumonia) 환자의 중증도 예측에 있어 프로칼시토닌 농도 측정의 유용성
Usefulness of Procalcitonin Levels in Assessing Severity in Patients with Healthcare-associated Pneumonia