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Meta Analysis for the Relation between Korean Dietary Factors and Stomach Cancer
°¡Á¤ÀÇÇÐȸÁö 2002³â 23±Ç 9È£ p.1098 ~ p.1106
±èÀ±Áø(Kim Youn-Jin) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¹éº´¿ø °¡Á¤ÀÇÇб³½Ç
±èöȯ(Kim Cheol-Hwan) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ °¡Á¤ÀÇÇаú
½É¼öÁ¤(Shim Su-Jung) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¹éº´¿ø °¡Á¤ÀÇÇб³½Ç
Abstract
¿¬±¸¹è°æ: ¼±Áø±¹¿¡¼´Â À§¾ÏÀÌ °¨¼ÒÇÏ°í ÀÖ´Â Ãß¼¼ÀÌÁö¸¸ ¾ÆÁ÷µµ ¿ì¸®³ª¶ó¿¡¼´Â ´ëÇ¥ÀûÀÎ ¾ÏÀÌ´Ù. À§¾ÏÀÇ À§ÇèÀÎÀÚ Áß °¢ ³ª¶óº°·Î ¹ß»ý·ü°ú »ç¸Á·üÀÇ Â÷À̸¦ ÃÊ·¡ÇÏ´Â °ÍÀº ½ÄÀÌ ¿äÀÎÀ¸·Î ¿ì¸®³ª¶ó »ç¶÷ÀÇ Æ¯Â¡ÀûÀÎ ½ÄÀÌ ¿äÀΰú À§¾Ï°úÀÇ °ü·Ã¼ºÀ»
ÃÖ±Ù±îÁö ¹ßÇ¥µÈ ³í¹®À» Åä´ë·Î ¸ÞŸ ºÐ¼®À» ÅëÇؼ Á¾ÇÕÇØ º¸°íÀÚ ÇÑ´Ù.
¹æ¹ý: 1995³â¿¡¼ 2002³â±îÁö Mediline°ú Pubmed¿¡ ¼ö·ÏµÈ °Í Áß ¿ì¸®³ª¶ó¿¡¼ ½ÄÀÌ ¿äÀΰú À§¾Ï¿¡ ´ëÇؼ ½ÃÇàÇÑ ³í¹®µéÀ» °Ë»öÇÏ¿´°í ¿ì¸®³ª¶ó¿¡¼ ½Ç¸° ³í¹® Áß ÀÚ¹®À» ¾ò¾î Çѱ¹¿ªÇÐȸÁö¿¡ ½Ç¸° ³í¹®À» °Ë»öÇÏ¿´´Ù. ±×Áß µÎ ÆíÀÇ ³í¹®À» Åä´ë·Î 14°³ÀÇ ½ÄÀÌ ¿äÀο¡ ´ëÇؼ Peto ¹æ¹ýÀ» ÀÌ¿ëÇÑ ¸ÞŸ ºÐ¼®À» ½ÃÇàÇÏ¿´´Ù.
°á°ú: 14°³ÀÇ ½ÄÀÌ ¿äÀÎ Áß ¼Ò±Ý ¼±È£(odds ratio 1.72 [95%CI 1.29~2.30] P<0.001), µÈÀå±¹(odds ratio 4.19 [95%CI 2.99~5.89] P<0.001), °íÃßÀå±¹(odds ratio 1.96 [95%CI 1.45~2.64] P<0.001), ±èÄ¡·ù(odds ratio 2.05 [95%CI 1.43~2.94] P<0.001), °í±ê±¹/»ý¼±±¹(odds ratio 1.58 [95%CI 1.17~2.13] P=0.003, ºÒ°í±â/»ý¼±±¸ÀÌ(odds ratio 1.84[95%CI 1.37~2.49] P<0.001), ÄáÀÚ¹Ý/¿°Àå½ÄÇ°(odds ratio 1.96[95%CI 1.47~2.61] P<0.001), ÈÇÐÁ¶¹Ì·á(odds ratio 2.55 [95%CI 0.14~0.31] P<0.001)´Â À§¾Ï¹ß»ýÀÇ À§Çè¿äÀÎÀ̾ú´Ù. ³ìµÎÀü (odds ratio 0.2 [95%CI 0.14~0.31] P<0.001), µÎºÎ(odds ratio 0.59 [95%CI 0.43~0.83] P<0.002), ¸¶´Ã(odds ratio 0.45 [95%CI 0.32~0.63] P<0.001) Àº À§¾Ï ¹ß»ýÀÇ ¿¹¹æ¿äÀÎÀ̾ú´Ù. °íÃå°¡·ç (odds ratio 1.21 [95%CI 0.91~1.63] P=0.19), ½Ò¹ä(odds ratio 1.39 [95%CI 0.87~2.2] P=0.16)Àº À§¾ÏÀÇ À§Çè¿äÀÎÀÓÀ» ½Ã»çÇßÁö¸¸ Åë°èÀûÀ¸·Î À¯ÀÇÇÏÁö´Â ¾Ê¾Ò°í, Âü±â¸§ ¼±È£(odds ratio 0.68 [95%CI 0.46~1.01] P=0.06)´Â À§¾ÏÀÇ ¿¹¹æ ¿äÀÎÀ» ½Ã»çÇßÁö¸¸ Åë°èÀûÀ¸·Î À¯ÀÇÇÏÁö ¾Ê¾Ò´Ù.
Background: The prevalence of stomach cancer had decreased in developed countries, but still remains high in Korea. There was an agreement that dietary factors were the most important factors in gastric carcinogenesis. We undertook a meta-analysis to verify the relation between Korean food items and stomach cancer.
Methods: We searched all studies compatible for meta-analysis by computer and by manual and found two studies. We analyzed 14 dietary factors presented in the two studies by Peto¡¯s method. We calculated summary odds ratios and test for homgeneity.
Results: Among the 14 dietary factors, salt preference (odds ratio 1.72 [95%CI 1.29~2.30] P<0.001), soybean paste stew (odds ratio 4.19 [95%CI 2.99~5.89] P<0.001), hot pepper soybean paste stew (odds ratio 1.96 [95%CI 1.45~2.64] P<0.001), Kimchi (odds ratio 2.05 [95%CI 1.43~2.94] P<0.001), meat/fish stew (odds ratio 1.58 [95%CI 1.17~2.13] P=0.003), Bulgogi/broiled fish (odds ratio 1.84 [95%CI 1.37~2.49] P<0.001), salted side dishes (odds ratio 1.96 [95%CI 1.47~2.61] P<0.001), and chemical seasoning (odds ratio 2.55 [95%CI 1.62~4.02] P<0.001) were risk factors to gastric cancer. But mung bean pancake (odds ratio 0.2 [95%CI 0.14~0.31] P<0.001), Dubu (odds ratio 0.59 [95%CI 0.43~0.83] P=0.002), and garlic (odds ratio 0.45 [95%CI 0.32~0.63] P<0.001) were preventable factors against gastric cancer. Red pepper (odds ratio 1.21 [95%CI 0.91~1.63] P=0.19) and boiled rice (odds ratio 1.39 [95%CI 0.87~2.2] P=0.16) were risk factors to gastric cancer, and sesame oil preference (odds ratio 0.68 [95%CI 0.46~1.01] P=0.06)was a preventable factor against gastric cancer, but these results were not statistically significant.
Å°¿öµå
À§¾Ï, ½ÄÀÌ¿äÀÎ, ¸ÞŸºÐ¼®, À§¾ÏÀ§Çè¿äÀÎ, À§¾Ï¿¹¹æ¿äÀÎ
meta-analysis, gastric cancer, dietary factor, risk factors, preventable factors
KMID :
0384320020230091098
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)
Red pepper (odds ratio 1.21 [95%CI 0.91~1.63] P=0.19) and boiled rice (odds ratio 1.39 [95%CI 0.87~2.2] P=0.16) were risk factors to gastric cancer, and sesame oil preference (odds ratio 0.68 [95%CI 0.46~1.01] P=0.06)was a preventable factor against gastric cancer, but these results were not statistically significant.