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The Clinical Characteristics and Prognosis of Elderly Patients with Lung Cancer Diagnosed in Daegu and Gyeongsangbukdo
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±èÇö¼÷(Kim Hyun-Sook) - ´ë±¸°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Àü¿µÁØ(Jeon Young-June) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Çѽ¹ü(Han Seung-Beom) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è°æÂù(Kim Kyung-Chan) - ´ë±¸°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
½Å°æö(Shin Kyeong-Cheol) - ¿µ³²´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¤ÁøÈ«(Chung Jin-Hong) - ¿µ³²´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÌ°üÈ£(Lee Kwan-Ho) - ¿µ³²´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Çö´ë¼º(Hyun Dae-Sung) - ´ë±¸°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÌ»óä(Lee Sang-Chae) - ´ë±¸°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¤Ä¡¿µ(Jung Chi-Young) - ´ë±¸ÆÄƼ¸¶º´¿ø ³»°ú
±è¿¬Àç(Kim Yeon-Jae) - ´ë±¸ÆÄƼ¸¶º´¿ø ³»°ú
Â÷½ÂÀÍ(Cha Seung-Ick) - °æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±èâȣ(Kim Chang-Ho) - °æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹ÚÀç¿ë(Park Jae-Yong) - °æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¤ÅÂÈÆ(Jung Tae-Hoon) - °æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÃÖ¿øÀÏ(Choi Won-Il) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÓ°ÇÀÏ(Lim Gune-Il) - ¼øõÇâ´ëÇб³ ±¸¹Ìº´¿ø ³»°ú
Abstract
Background: Lung cancer is the leading cause of cancer death in South Korea since the year 2000 and it is more
common in elderly patients, with a peak incidence at around 70¡80 years of age. However, these elderly patients receive treatment less often than do the younger patients because of organ dysfunction related to their age and their comorbidities, and they show poor tolerance to chemotherapy. The aims of this study were to analyze the clinical characteristics and treatment-related survival of elderly patients with lung cancer.
Methods: In this retrospective study, we analyzed the clinical data of 706 lung cancer patients who were diagnosed at hospitals in Daegu and Gyeongsangbukdo from January 2005 to December 2005. We compared the clinical
characteristics and outcomes of the patients who were aged 70 years and older (elderly patients) with those clinical
characteristics and outcomes of the younger individuals.
Results: The median age of the patients was 68 years (from 29 to 93) and the elderly patients were 38.7% (n=273)
of all the study¡¯s patients. Squamous cell carcinoma was the most common type of lung cancer in both the elderlyband younger patient groups. Elderly patients had more symptoms of dyspnea and chronic obstructive pulmonary disease (COPD) than the younger patients (p£¼0.001 and p£¼0.001, respectively). A good performance status (ECOG 0-1) was less common for the elderly patients (p£¼0.001). The median survival of the non-small cell lung cancer (NSCLC) patients was significantly higher in the younger patient group than in the elderly patient group (962 days vs 298 days, respectively, p=0.001). However, the median survival of the NSCLC patients who received any treatment showed no significant difference between the younger patient group and the elderly patient group (1,109 days vs 708 days, respectively, p=0.14).
Conclusion: Our data showed that appropriate treatment for selected elderly patients improved the survival of
patients with NSCLC. Therefore, elderly NSCLC patients with a good performance status should be encouraged to receive appropriate treatment. (Tuberc Respir Dis 2008;65:15-22)
Å°¿öµå
Elderly patients, Lung cancer
KMID :
0383820080650010015
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À¯È¿¼º°á°ú(Recomendation)
elderly NSCLC patients with a good performance status should be encouraged to receive appropriate treatment; The median survival of the non-small cell lung cancer (NSCLC) patients was significantly higher in the younger patient group than in the elderly patient group (962 days vs 298 days, respectively, p=0.001). However, the median survival of the NSCLC patients who received any treatment showed no significant difference between the younger patient group and the elderly patient group (1,109 days vs 708 days, respectively, p=0.14).