Aortic Aneurysm Screening in a High-Risk Population: A Non-Contrast Computed Tomography Study in Korean Males with Hypertension
Korean Circulation Journal 2014³â 44±Ç 3È£ p.162 ~ p.169
Á¶ÀÎÁ¤(Cho In-Jeong) - Yonsei Cardiovascular Hospital and Cardiovascular Research Institute Cardiology Division
À强¿(Jang Sung-Yeol) - Yonsei University College of Medicine Severance Cardiovascular Hospital Cardiology Division
ÀåÇõÀç(Chang Hyuk-Jae) - Yonsei University College of Medicine Severance Cardiovascular Hospital Cardiology Division
½Å»óÈÆ(Shin Sang-hoon) - Yonsei University Health System Severance Cardiovascular Hospital Division of Cardiology
½ÉÁö¿µ(Shim Chi-Young) - Yonsei University College of Medicine Yonsei Cardiovascular Hospital Division of Cardiology
È«±×·ç(Hong Geu-Ru) - Yonsei University College of Medicine Severance Cardiovascular Hospital Cardiology Division
Á¤³²½Ä(Chung Nam-Sik) - Yonsei University College of Medicine Yonsei Cardiovascular Hospital Division of Cardiology
Abstract
Background and Objectives: Screening strategies for aortic aneurysm (AA) according to risk factors and ethnicity are controversial. This study explored the prevalence of AA and determined whether screening is necessary in a population of multiple risk factors.
Subjects and Methods: From June, 2012 to April, 2013, 542 consecutive elderly (¡Ã65 years) male hypertensive patients without a history of AA were prospectively enrolled. After excluding 15 patients (2.8%) with aortic valve surgery, 30 patients (5.5%) with suboptimal computed tomography (CT) images, the remaining 496 patients (age 73¡¾5 years) comprised the study population. Maximal diameters of the thoracic and abdominal aorta were measured using non-contrast CT.
Results: The prevalence of thoracic AA (TAA, diameter ¡Ã40 mm) and abdominal AA (AAA, diameter ¡Ã30 mm) was 36.5% (181/496) and 6.0% (30/496), respectively. In the multivariate logistic regression analysis, determinants for TAA were age {odds ratio (OR) 1.059, 95% confidence interval (CI) 1.018-1.101, p=0.005}, dyslipidemia (OR 0.621, 95% CI 0.418-0.923, p=0.018), body surface area (OR 11.92, 95% CI 2.787-50.97, p=0.001), diastolic blood pressure (OR 1.029, 95% CI 1.009-1.049, p=0.004) and AAA (OR 3.070, 95% CI 1.398-6.754, p=0.005). In contrast, AAA was independently associated with dysplipidemia (OR 2.792, 95% CI 1.091-7.143, p=0.032), current/past smokerfs (OR 4.074, 95% CI 1.160-14.31, p=0.028), and TAA (OR 3.367, 95% CI 1.550-7.313, p=0.002).
Conclusion: The prevalence of AA was significant and TAA was more prevalent than AAA in elderly Korean males with hypertension. Future research should establish distinct screening strategies for TAA and AAA according to risk factors and ethnicity.
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Aorta, Aneurysm, Prevalence, Computed tomography
KMID :
0368120140440030162
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