Aortic Valve Replacement for Aortic Stenosis and Concomitant Coronary Artery Bypass: Long-term Outcomes and Predictors of Mortality

대한흉부외과학회지 2011년 44권 2호 p.131 ~ p.136

조원철(Cho Won-Chul) - University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery
유동곤(Yoo Dong-Gon) - University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery
김준범(Kim Joon-Bum) - University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery
이제원(Lee Jae-Won) - University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery
주석중(Choo Suk-Jung) - University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery
정성호(Jung Sung-Ho) - University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery
정철현(Chung Cheol-Hyun) - University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery

Abstract

Background: We evaluated the surgical results and predictors of long-term survival in patients who underwent coronary artery bypass grafting (CABG) at the time of an aortic valve replacement (AVR) due to aortic stenosis.

Materials and Methods: Between January 1990 and December 2009, 183 consecutive patients underwent CABG and concomitant aortic valve replacement for aortic stenosis. The mean follow-up period was 59.8±3.3 months and follow-up was possible in 98.3% of cases. Predictors of mortality were determined by Cox regression analysis.

Results: There were 5 (2.7%) in-hospital deaths. Follow-up of the in-hospital survivors documented late survival rates of 91.5%, 74.8%, and 59.6% at 1, 5, and 10 postoperative years, respectively. Age (p<0.001), a glomerular filtration rate (GFR) less than 60 mL/min (p=0.006), and left ventricular (LV) mass (p<0.001) were significant predictors of mortality in the multivariate analysis.

Conclusion: The surgical results and long-term survival of aortic valve replacement with concomitant CABG in patients with aortic stenosis and coronary artery disease were acceptable. Age, a GFR less than 60 mL/min, and LV mass were significant predictors of mortality.

키워드

Aortic valve stenosis, Coronary artery disease, Coronary artery bypass surgery
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학술진흥재단(KCI) KoreaMed 대한의학회 회원 
주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
The surgical results and long-term survival of aortic valve replacement with concomitant CABG in patients with aortic stenosis and coronary artery disease were acceptable.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
KCD코드
ICD 03
건강보험코드