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Regression of Left Ventricular Mass after Aortic Valve Replacement in Isolated Aortic Regurgitation

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À̼®¼ö(Lee Seok-Soo) - ¿µ³²´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç

Abstract

¹è°æ: ´Üµ¶ ´ëµ¿¸ÆÆǸ· Æó¼âºÎÀüÁõ(AR) ȯÀÚ¿¡¼­ ´Üµ¶ ´ëµ¿¸ÆÆǸ· ġȯ¼ú ÈÄ Á½ɽÇÁú·® °¨¼ÒÀÇ Á¤ µµ¸¦ Æò°¡ÇÏ°íÀÚ ÇÏ¿´´Ù.

´ë»ó ¹× ¹æ¹ý: 2002³âºÎÅÍ 2007³â±îÁö ´ëµ¿¸ÆÆǸ· Æó¼âºÎÀüÁõÀ¸·Î ´Ü¼ø ´ë µ¿¸ÆÆǸ· ġȯ¼úÀ» ½ÃÇàÇÑ 20¸íÀ» ´ë»óÀ¸·Î ¼ö¼ú Àü°ú ¼ö¼ú ÈÄ 1³â¿¡ ½ÉÃÊÀ½ÆÄ °Ë»ç°á°ú¸¦ ÈÄÇâÀûÀ¸ ·Î Á¶»çÇÏ¿´´Ù. ´ë»óȯÀÚ´Â ³²ÀÚ 12¸í, ¿©ÀÚ 8¸í, Æò±Õ¿¬·É 55.8¡¾11.8¼¼, Æò±Õüǥ¸éÀû 1.64¡¾0.19 m2ÀÌ ¾ú´Ù. ´ëÁ¶±ºÀº ½ÉÃÊÀ½ÆÄ»ó º´º¯ÀÌ ¹ß°ßµÇÁö ¾ÊÀº ºñ½ÁÇÑ ³ªÀÌÀÇ 41¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´´Ù. ´ëµ¿¸ÆÆÇ ¸· ġȯ¼ú ÀÌ¿ÜÀÇ º¹ÇսüúÀ» ½ÃÇàÇÑ È¯ÀÚ¿Í °¨¿°¼º ½É³»¸·¿° ȯÀÚ´Â Á¦¿ÜÇÏ¿´´Ù.

°á°ú: ¼ö¼ú¿¡ »ç¿ë µÈ ÆǸ·ÀÇ Á¾·ù´Â Á¶Á÷ÆǸ·ÀÌ 7¸í, ±â°èÆǸ·ÀÌ 13¸í¿¡¼­ »ç¿ë µÇ¾úÀ¸¸ç Å©±â´Â 21 mm°¡ 3¸í, 23 mm °¡ 13¸í ±×¸®°í 25 mm°¡ 4¸í¿¡¼­ »ç¿ëµÇ¾ú´Ù. ¼ö¼ú ÈÄ Á½ɽÇÁú·®°è¼ö(LVMI, 125.5¡¾42 g/m2)´Â ¼ú Àü¿¡ ºñÇØ À¯ÀÇÇÏ°Ô °¨¼ÒÇÏ¿´À¸³ª(212.3¡¾80 g/m2, p=0.000) ´ëÁ¶±º(80.5¡¾15.9 g/m2, p=0.000)¿¡ ºñÇØ ³ô ¾Ò´Ù. ¼ö¼ú ÀüÈÄÀÇ ½É½ÇÁß°Ý(È®Àå±â/¼öÃà±â: 13.5¡¾3.4 mm/17.1¡¾4.1 mm)°ú ÁÂ½É½Ç Èĺ®(È®Àå±â/¼öÃà±â: 12.9¡¾3.4 mm/16.7¡¾3.4 mm)ÀÇ µÎ²²´Â ¼ö¼ú Àü¿¡ ºñÇØ ÀϺΠ°¨¼Ò°¡ ÀÖ¾úÀ¸³ª Åë°èÀûÀ¸·Î À¯ÀÇÇÏÁö ¾Ê ¾ÒÀ¸¸ç °¢°¢ ´ëÁ¶±º(È®Àå±â/¼öÃà±â: 8.6¡¾1.4 mm/12.1¡¾1.7 mm, È®Àå±â/¼öÃà±â: 8.4¡¾1.4 mm/13.2¡¾1.9 mm)º¸´Ù À¯ÀÇÇÏ°Ô ³ô¾Ò´Ù(p£¼0.001).

°á·Ð: ´Üµ¶ ´ëµ¿¸ÆÆǸ· Æó¼âºÎÀüÀ¸·Î ´Üµ¶ ´ëµ¿¸ÆÆǸ· ġȯ¼ú ½ÃÇà 1³â ÈÄ ÁÖ·Î Á½ɽǿëÀûÀÇ °¨¼Ò¿¡ ÀÇÇÑ LVMIÀÇ À¯ÀÇÇÑ °¨¼Ò°¡ ÀÖ¾úÀ¸³ª ´ëÁ¶±º¿¡ ºñÇؼ­´Â ¿©ÀüÈ÷ ³ô¾Ò´Ù.
Background: The aim of our study was to assess the extent of regression of left ventricular mass after aortic valve replacement in isolated aortic regurgitation.

Material and Method: Retrospective analysis of echocardiographic data was collected preoperative and postoperative 1 year. There were 20 patients (12 males, 8 females, mean age 55.8¡¾11.8 years, mean body surface area 1.64¡¾0.19 m2) with aortic regurgitation from 2002 through 2007. We studied the change of left ventricular ejection fraction, ventricular septum and left ventricular posterior wall thickness, and left vemtricular muscle index (LVMI). The control group was age matched with normal echocardiographic study results. Patients with combined surgery or infective endocarditis were excluded.

Result: Seven cases of tissue valves and thirteen cases of mechanical valve were used. The valve sizes were 21 mm (3 cases), 23 mm (13 cases) and 25 mm (4 cases). The postoperative (125.5¡¾42 g/m2) LVMI has decreased than preoperative LVMI (212.3¡¾80 g/m2, p=0.000) but higher than that of control group (80.5¡¾15.9 g/m2, p=0.000). Postoperative septal wall (systolic/diastolic: 13.5¡¾3.4 mm/17.1¡¾4.1 mm) and left ventricular posterior wall (systolic/diastolic: 12.9¡¾3.4 mm/16.7¡¾ 3.4 mm) thickness were slightly decreased after the valve replacement but was not significantly different than preoperative levels. And postoperative interventricular septal wall and left ventricular posterior wall thickness (systolic/diastolic: 8.6¡¾1.4 mm/12.1¡¾1.7 mm, systolic/diastolic: 8.4¡¾1.4/13.2¡¾1.9) were higher than that of the control group (p£¼0.001).

Conclusion: The significant regression of LVMI after aortic valve replacement developed at postoperative one year but the level was higher than control group. The main cause of decreased LVMI is decreased in left ventricular dimension.

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ÆǸ·Áúȯ, ´ëµ¿¸ÆÆǸ·Æó¼âºÎÀü, Àΰø½ÉÀåÆǸ·
Valve disease, Aortic valve insufficiency, Heart valve prosthesis
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ÇмúÁøÈïÀç´Ü(KCI) KoreaMed ´ëÇÑÀÇÇÐȸ ȸ¿ø 
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´ë»ó¼ºº°(Gender)
Áúº´Æ¯¼º(Condition Category)
¿¬±¸È¯°æ(Setting)
¿¬±¸¼³°è(Study Design)
¿¬±¸±â°£(Period)
ÁßÀç¹æ¹ý(Intervention Type)
ÁßÀç¸íĪ(Intervention Name)
Å°¿öµå(Keyword)
À¯È¿¼º°á°ú(Recomendation)
The postoperative (125.5¡¾42 g/m2) LVMI has decreased than preoperative LVMI (212.3¡¾80 g/m2, p=0.000) but higher than that of control group (80.5¡¾15.9 g/m2, p=0.000). Postoperative septal wall (systolic/diastolic: 13.5¡¾3.4 mm/17.1¡¾4.1 mm) and left ventricular posterior wall (systolic/diastolic: 12.9¡¾3.4 mm/16.7¡¾ 3.4 mm) thickness were slightly decreased after the valve replacement but was not significantly different than preoperative levels.
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±Ù°Å¼öÁØÆò°¡(Evidence Hierarchy)
ÃâÆdz⵵(Year)
Âü¿©ÀúÀÚ¼ö(Authors)
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DOI
KCDÄÚµå
ICD 03
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