ÀüÀ̼º Æó¾ÏÀÇ ¿Ü°úÀû Ä¡·á
Surgical Treatment of Pulmonary Metastases

´ëÇÑÈäºÎ¿Ü°úÇÐȸÁö 2007³â 40±Ç 2È£ p.103 ~ p.108

°­Á¤È£(Kang Jung-Ho) - ÇѾç´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç
³ë¼±±Õ(Ro Sun-Kyun) - ÇѾç´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç
±è¿µÇÐ(Kim Young-Hak) - ÇѾç´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç
Á¤¿ø»ó(Chung Won-Sang) - ÇѾç´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç
±èÇõ(Kim Hyuck) - ÇѾç´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç
¹Ýµ¿±Ô(Ban Dong-Gyu) - ÇѾç´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç

Abstract

¹è°æ: ¿©·¯ °¡Áö °íÇü¾ÏÀ¸·ÎºÎÅÍ ÀüÀÌµÈ Æó¾Ï ȯÀÚ¿¡ À־ ¼ö¼úÀû ÀýÁ¦´Â Áß¿äÇÑ Ä¡·á ¹æ¹ý Áß Çϳª´Ù. À̸¦ Åä´ë·Î º»¿ø¿¡¼­ 1996³âºÎÅÍ 2005³â±îÁö 37¸íÀÇ È¯ÀÚ¿¡¼­ ½ÃÇàÇÑ ÀüÀ̼º Æó¾ÏÀÇ ¼ö¼úÀû Ä¡·á¿¡ ´ëÇØ ºÐ¼®ÇØ º¸°íÀÚ ÇÑ´Ù.

´ë»ó ¹× ¹æ¹ý: ȯÀÚÀÇ ÀÔ¿ø±â·Ï°ú ¼ö¼ú±â·Ï, º´¸®±â·ÏÁö µîÀ» ÅëÇÏ¿© ³ªÀÌ, ¼ºº°, ¹«º´»ýÁ¸±â°£, ¼ö¼ú ¹æ¹ý, Æó ÀüÀÌ º´¼Ò °³¼ö, ¸²ÇÁÀý ÀüÀÌ ¿©ºÎ µîÀ» Á¶»çÇÏ¿´´Ù. »ýÁ¸ °î¼±°ú »ýÁ¸À² °£ÀÇ ºñ±³´Â °¢°¢ Kaplan-Meier life table°ú log-rank test¸¦ ÀÌ¿ëÇÏ¿´´Ù.

°á°ú: 37¸íÀÇ È¯ÀÚ Áß 34¸í¿¡¼­ ¿ÏÀü ÀýÁ¦°¡ °¡´ÉÇÏ¿´´Ù. ¿ø¹ß Á¾¾çÀº ¾ÏÁ¾ÀÌ 25¸í, À°Á¾ÀÌ 10¸í, ´Ù¸¥ Á¾·ù°¡ 2¸íÀ̾úÀ¸¸ç Æó ÀüÀÌ °³¼ö´Â 1°³°¡ 25¸í, 2°³ ÀÌ»óÀÌ 12¸íÀ̾ú´Ù. ¿ÏÀü ÀýÁ¦°¡ °¡´ÉÇß´ø ȯÀÚ ±º¿¡¼­ ¼ö¼ú ÈÄ 3³â »ýÁ¸À²Àº 50.5%, 5³â »ýÁ¸À²Àº 35.9%À¸·Î ³ªÅ¸³µ´Ù. ¿ø¹ß Á¾¾çÀÇ Á¾·ù¿¡ µû¶ó »ýÁ¸À²À» ºñ±³ÇÏ¿´À» ¶§ ¾ÏÁ¾¿¡¼­ÀÇ 3³â »ýÁ¸À²Àº 64.5%, 5³â »ýÁ¸À²Àº 45.6%·Î ³ªÅ¸³µÀ¸³ª À°Á¾¿¡¼­ÀÇ 3³â »ýÁ¸À²Àº 17.5%·Î ³·°Ô ³ªÅ¸³µ´Ù. ¹Ý¸é, ¼ö¼ú ¹æ¹ý, Æó ÀüÀÌ °³¼ö, ¸²ÇÁÀý ÀüÀÌ ¿©ºÎ, Ãß°¡ Ç×¾ÏÄ¡·á ¿©ºÎ¿Í ¾ÏÁ¾¿¡¼­ ¹«º´»ýÁ¸ ±â°£ µîÀº »ýÁ¸À²¿¡ À¯ÀÇÇÏ°Ô ¿µÇâÀ» ¹ÌÄ¡Áö ¸øÇß´Ù.

°á·Ð: ÀüÀ̼º Æó¾ÏÀº ¿ÏÀü ÀýÁ¦°¡ °¡´ÉÇÒ °æ¿ì Àß ¼±ÅÃµÈ ÀϺΠȯÀÚ¿¡¼­ ¼ö¼ú¿¡ µû¸¥ »ç¸Á·üÀ̳ª ÀÌȯÀ²Àº ³·À¸¸é¼­µµ ³ôÀº Àå±â »ýÁ¸À²À» ±â´ëÇÒ ¼ö ÀÖ´Â ÁúȯÀÌ´Ù. ÀüÀ̼º Æó¾ÏÀÇ ¼ö¼ú ÈÄ ¿¹ÈÄÀÎÀÚ µî¿¡ ´ëÇÑ Â÷ÈÄ Àå±âÀûÀÎ ÃßÀû°üÂû°ú ¹«ÀÛÀ§ ÀüÇâÀû ºñ±³ ¿¬±¸ µîÀÌ ´õ ÇÊ¿äÇÒ °ÍÀ¸·Î º¸ÀδÙ.
Background: Surgical resection is an important modality in the treatment of pulmonary metastases from various solid tumors. We analyzed 37 patients who underwent surgical treatments of pulmonary metastases in our hospital from 1996 to 2005.

Materials & Methods: Age, sex, disease free interval, operative procedure, the number of pulmonary metastases, and lymphatic metastasis were investigated with admission and operative records, and pathologic reports. Actuarial survival and comparisons between each survival rate were calculated according to Kaplan- Meier method and log-rank test, respectively.

Results: Complete resections were carried out in 34 of 37 patients. The primary tumor was carcinoma in 25 cases, sarcoma in 10, and others in 2. The number of pulmonary metastases was 1 in 25 cases and 2 or more in 12 cases. 3-year and 5-year survival rates after complete resection were 50.5% and 35.9%, respectively. 3-year and 5-year survival rates for carcinoma were 64.5% and 45.6%, respectively, and 3-year survival rate for sarcoma was 17.5%. Otherwise, none of the operative procedures, the number of pulmonary metastases, lymphatic metastasis, adjunctive therapy and the disease free interval in the case of carcinoma significantly affected the survival rates.

Conclusion: Complete resection of pulmonary metastasis in well selected patients allows high long term survival rate with low mortality and morbidity. Long-term follow up and randomized prospective studies were necessary to determine the prognostic factors of pulmonary metastases after surgical resection.

Å°¿öµå

ÀüÀÌ¾Ï ÀýÁ¦¼ú, ¾Ç¼º ÀüÀÌ, »ýÁ¸ ºÐ¼®
Metastasectomy, Neoplasm metastasis, Survival analysis
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
ÇмúÁøÈïÀç´Ü(KCI) KoreaMed ´ëÇÑÀÇÇÐȸ ȸ¿ø 
ÁÖÁ¦ÄÚµå
ÁÖÁ¦¸í(Target field)
¿¬±¸´ë»ó(Population)
¿¬±¸Âü¿©(Sample size)
´ë»ó¼ºº°(Gender)
Áúº´Æ¯¼º(Condition Category)
¿¬±¸È¯°æ(Setting)
¿¬±¸¼³°è(Study Design)
¿¬±¸±â°£(Period)
ÁßÀç¹æ¹ý(Intervention Type)
ÁßÀç¸íĪ(Intervention Name)
Å°¿öµå(Keyword)
À¯È¿¼º°á°ú(Recomendation)
Complete resection of pulmonary metastasis in well selected patients allows high long term survival rate with low mortality and morbidity.
¿¬±¸ºñÁö¿ø(Fund Source)
±Ù°Å¼öÁØÆò°¡(Evidence Hierarchy)
ÃâÆdz⵵(Year)
Âü¿©ÀúÀÚ¼ö(Authors)
´ëÇ¥ÀúÀÚ
DOI
KCDÄÚµå
ICD 03
°Ç°­º¸ÇèÄÚµå