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Three Cases of Generalized Granuloma Annulare in Infancy Following Bacillus Calmette-Guerin Vaccination

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±è¼­¿Ï(Kim Seo-Wan) - Eulji University College of Medicine Department of Dermatology
°øÅ¼®(Kong Tae-Seok) - Eulji University College of Medicine Department of Dermatology
ÇÑÅ¿µ(Han Tae-Young) - Eulji University College of Medicine Department of Dermatology
ÀÌÇö°æ(Lee Hyun-Kyung) - Eulji University College of Medicine Department of Dermatology
¼Õ¼÷ÀÚ(Son Sook-Ja) - Eulji University College of Medicine Department of Dermatology

Abstract

Generalized granuloma annulare is a rare benign granulomatous dermatosis characterized by disseminated necrobioticdermal papules forming an annular or nonannular configuration. It usually occurs in adults and rarely affects infants. Histologically, it presents as a lymphohistiocytic granuloma associated with varying degrees of connective tissue degeneration. Clinical associations between generalized granuloma annulare and diabetes mellitus, thyroid disease,malignancy, infection, and vaccination have been reported. There are a few cases reports of generalized granulomaannulare associated with Bacillus Calmette-Guerin (BCG) vaccination. Herein, we report three cases of generalizedgranuloma annulare following BCG vaccination in infants.

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BCG vaccine, Granuloma annulare, Infant
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