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비소세포성페암에서 방사선치료단독요법과 항암제 병합요법과의 치료결과 비교
Therapeutic Results of Radiation Therapy Alone and Combination with Chemotherapy in Non-Small Cell Lung Carcinoma

대한치료방사선과학회지 1993년 11권 2호 p.303 ~ p.309

김주리(Kim Ju-Ree) - 인제대학교 의과대학 서울백병원 치료방사선과학교실
서현숙(Suh Hyun-Suk) - 인제대학교 의과대학 서울백병원 치료방사선과학교실

Abstract

Between November 1983 and December 1992, 121 patients with non-small cell lung cancer were treated with radiotherapy alone or combined with chemotherapy in Inje University, Seoul Paik Hospital.
Of these, 97 patients were evaluable and analyzed retrospectively. Group 1(n=62) was treated with radiotherapy alone and group 2(n=35) combined with chemotherapy. There were 7 patients, 1 patient with stage I and Ⅱ, 20 patients, 11 patients with stage ⅢA, 28 patients,20 patients with stage ⅢB, and 6 patients, 3 patients with stage IV, respectively. Ninety percent of patients received more than 5000 cGy of radiaton.
Median survival of patients in group 1 was 9 months, group 2 was 15 months. Overall 2 year survival rates of group 1 and 2 were 37% and 27%, respectively. Relapse free survival rates at 2 year were 27% and 15%, respectively. Overall survival rates at 5 year for group 1 and 2 were 15% and 11%, and relapse free survival rates were 16% and 6%, respectively.
Median survival of complete and partial responders was 17 months in group 1, 18 Months in group 2, and those of stable or progression was 6 mouths, 11 months, respectively.
The proportion of locoregional relapse and distant metastasis was not significantly different between group 1 and 2. The majority of relapse developed within 2 years.
Although 2 cases of severe esophagitis and myelosuppression were noted in group 2, the treatment related toxicity was relatively acceptable.
Our analysis showed no statistically significant differences between the two treatment groups in terms of response rate, survival, and sites of relapse.

키워드

Non-small cell lung carcinoma, Radiotherapy alone, Combined modality with radiotherapy and chemotherapy

KMID : 0362919930110020303

원문 및 링크아웃 정보

등재저널 정보

주제코드

주제명(Target field)

연구대상(Population)

연구참여(Sample size)

대상성별(Gender)

질병특성(Condition Category)

연구환경(Setting)

연구설계(Study Design)

연구기간(Period)

중재방법(Intervention Type)

중재명칭(Intervention Name)

키워드(Keyword)

유효성결과(Recomendation)

No statistically significant differences between the two treatment groups in terms of response rate, survival, and sites of relapse.

연구비지원(Fund Source)

근거수준평가(Evidence Hierarchy)

출판년도(Year)

참여저자수(Authors)

대표저자

DOI

KCD코드

ICD 03

건강보험코드

비소세포성페암에서 방사선치료단독요법과 항암제 병합요법과의 치료결과 비교 Therapeutic Results of Radiation Therapy Alone and Combination with Chemotherapy in Non-Small Cell Lung Carcinoma

Abstract

키워드

비소세포성페암에서 방사선치료단독요법과 항암제 병합요법과의 치료결과 비교
Therapeutic Results of Radiation Therapy Alone and Combination with Chemotherapy in Non-Small Cell Lung Carcinoma