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Postoperative Radiation Therapy in Non-Small-Cell Lung Cancer
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¹ÚÂùÀÏ(Park Charn-Il) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ Ä¡·á¹æ»ç¼±°ú
±èÁ¾ÈÆ(Kim Jong-Hoon) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ Ä¡·á¹æ»ç¼±°ú
±èÁÖÇö(Kim Joo-Hyun) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ÈäºÎ¿Ü°úÇб³½Ç
Abstract
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Àüü ȯÀÚ 60¸íÁß ¹æ»ç¼± Ä¡·á¸¦ ºÒ¿ÏÀüÇÏ°Ô ½ÃÇàÇÑ 5¸íÀ» Á¦¿ÜÇÑ 55¸íÀ» ºÐ¼®ÇÑ °á°ú Àüü ȯÀÚÀÇ 5³â »ýÁ¸À²Àº 39%¿´À¸¸ç ¹«º´»ýÁ¸À²Àº 29%¿´´Ù. ȯÀÚÀÇ ¿¹Èĸ¦ °áÁ¤ÇÏ´Â ÁÖ¿äÀÎÀڷμ´Â º´±â ¹× ±¹¼Ò ÀÓÆÄÀý ÀüÀÌ ¿©ºÎ¿´°í, Tº´±â¿Í º´¸®Á¶Á÷ÇÐÀû ºÐ·ù ¹× ³ªÀÌ, ¼ºº°, ¹æ»ç¼± Á¶»ç¼±·®°ú ¼ö¼ú½Ã ÀýÁ¦¸éÀÇ Á¾¾ç ħ¹ü ¿©ºÎ´Â ¿¹ÈÄ¿¡ Å« ¿µÇâÀ» ¹ÌÄ¡Áö ¸øÇÏ¿´´Ù. ¼ö¼ú ½ÃÇàÈÄ ¹æ»ç¼± Ä¡·á¸¦ ¹ÞÀº ȯÀÚ±ºÀÇ »ýÁ¸À²Àº, ¹®Çå»ó¿¡ ³ªÅ¸³ ¼ö¼ú ´Üµ¶ ½ÃÇà ȯÀÚ±ºÀÇ »ýÁ¸·ü°ú ºñ±³ÇØ º¼ ¶§ ±¹¼Ò ÀÓÆÄÀý ÀüÀÌ°¡ Àִ ȯÀÚ±º¿¡¼ ´õ ³ôÀº °á°ú¸¦ º¸¿´À¸¸ç, ÀÓÆÄÀý ÀüÀÌ°¡ ¾ø´Â ȯÀÚ±º¿¡¼´Â Å« Â÷À̸¦ ¹ß°ßÇÒ ¼ö ¾ø¾ú´Ù.
±¹¼Ò Àç¹ßÀ²µµ ÀÓÆÄÀý ÀüÀÌ°¡ Àִ ȯÀÚ±º¿¡¼´Â ¼ö¼ú ´Üµ¶ ½ÃÇà ȯÀÚ±ºº¸´Ù ÇöÀúÈ÷ ³·Àº °á°ú¸¦ º¸¿© ¼ö¼úÈÄ ¹æ»ç¼± Ä¡·á°¡ ÀÓÆÄÀý ÀüÀÌ°¡ Àִ ȯÀÚ¿¡¼´Â »ýÁ¸À²ÀÇ Áõ°¡ ¹× ±¹¼ÒÀç¹ß ¾ïÁ¦ÀÇ È¿°ú¸¦ ³ªÅ¸³¿À» °üÂûÇÒ ¼ö ÀÖ¾ú´Ù.
Sixty patients with proven lung cancer were retrospectively studied to determine whether postoperative radiation therapy improves survival. Patterns of treatment failure and 5 year survival were assessed according to extent of tumor spread, histology, type of operation, positive resection margin and radiation dose.
Of the 60 patients, excluding 5 patients who received incomplete treatment of poor pulmonary function, 55 patients received postoperative radiation therapy following curative resection. The overall survivial at 5 years was 39%. The hilar and mediasinal lymph node involvement had an influence on survival. The authors recommend that patients with resectable lung cancer involving the hilar and mediastinal lymph nodes may require postoperative radiotherapy to reduce the local recurrence and improve survival.
Å°¿öµå
Postoperative radiation therapy, Lung cancer, Lymph node
KMID :
0362919880060020195
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À¯È¿¼º°á°ú(Recomendation)
The overall survivial at 5 years was 39%.