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The treatment Results of Radiotherapy for nonsmall Cell Lung Cancer
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À±Á¾Ã¶(Yoon Jong-Chul) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¹éº´¿ø Ä¡·á¹æ»ç¼±°úÇб³½Ç
¼Õ½Ââ(Sohn Seung-Chang) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¹éº´¿ø Ä¡·á¹æ»ç¼±°úÇб³½Ç
¼Çö¼÷(Suh Hyun-Suk) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¹éº´¿ø Ä¡·á¹æ»ç¼±°úÇб³½Ç
Àü¿ì±â(Jaun Woo-Ki) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¹éº´¿ø Áø´Ü¹æ»ç¼±°ú
±èµ¿¼ø(Kim Dong-Soon) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¹éº´¿ø ³»°ú
¼Õ±¤Çö(Sohn Kwang-Hyun) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ¹éº´¿ø ÈäºÎ¿Ü°ú
Abstract
1983³â 11¿ùºÎÅÍ 1986³â 1¿ù±îÁö ÀÎÁ¦ÀÇ´ë ºÎ¼Ó ¹éº´¿ø Ä¡·á¹æ»ç¼±°ú¿¡¼ 43¸íÀÇ ºñ ¼Ò¼¼Æ÷¼º Æó¾Ï ȯÀÚ¸¦ Ä¡·áÇÏ¿´´Ù. ±×Áß¿¡¼ ºÐ¼® °¡´ÉÇÑ 38¸í¿¡ ´ëÇÑ Ä¡·á°á°ú¸¦ º¸°íÇÏ´Â ¹ÙÀÌ´Ù.
33¸íÀÌ ±ÙÄ¡Àû ¸ñÀûÀ¸·Î ¹æ»ç¼± Ä¡·á¸¦ ¹Þ¾Ò°í ³ª¸ÓÁö 5¸íÀº ¼ö¼úÈÄ ¹æ»ç¼± Ä¡·á¸¦ ¹Þ¾Ò´Ù. 12¸íÀÇ È¯ÀÚ´Â ¹æ»ç¼± Ä¡·áÇϱâÀü ȤÀº ¹æ»ç¼±Ä¡·á¿Í ´õºÒ¾î, ±×¸®°í ¹æ»ç¼± Ä¡·áÈÄ¿¡ ¾à¹°Ä¡·á¸¦ º´ÇàÇÏ¿´´Ù.
38¸íÀÇ È¯ÀÚÁß 28¸íÀÌ ÆíÆò»óÇÇÁ¾À̾ú°í 10¸íÀº ¼±Á¾À̾ú´Ù. ³²ÀÚ È¯ÀÚ°¡ 29¸í, ¿©ÀÚ È¯ÀÚ°¡ 9¸íÀ̾ú°í Æò±Õ ³ªÀÌ´Â 58¼¼·Î 34¼¼·ÎºÎÅÍ 74¼¼±îÁöÀÇ ºÐÆ÷¸¦ º¸¿´´Ù. º´±âº°·Î º¸¸é 1±â°¡ 1¸í, 2±â°¡ 7¸í, ±×¸®°í 3±â°¡ 30¸íÀ̾ú´Ù.
±ÙÄ¡Àû ¸ñÀûÀ¸·Î Ä¡·áÇÑ È¯ÀÚÁß Ä¡·áÈÄ ÈäºÎ X-¼±»çÁø°ú ÄÄÇ»ÅÍ ´ÜÃþÃÔ¿µ»ó¿¡¼ ¿ÏÀüÈ÷ Á¾¿ëÀÌ ¼Ò½ÇµÈ °æ¿ì°¡ 36%, 50% ÀÌ»óÀÇ Á¾¾çÅ©±â °¨¼Ò¸¦ º¸ÀÎ °æ¿ì°¡ 27%, 25%ÀÌ»óÀÇ Á¾¾çÅ©±â °¨¼Ò¸¦ º¸ÀÎ °æ¿ì°¡ 15%¿´°í ¹ÝÀÀÀ» º¸ÀÌÁö ¾ÊÀº °æ¿ì°¡ 21%¿´´Ù.
From Nov. 1983 through Jan. 1986, 43 patients with nonsmall cell lung cancer were treated by radiation therapy at Inje Medical College Paik Hospital. 38 patients were available for the analysis of this study. 33 patients received definite irradiation with curative intent, while 5 patients received postoperative irradion. Chemotherapy was added in 12 patients before, during and after radio-therapy. 28 patients were squamous cell carcinoma and 10 patients were adenocarcinoma. There were 29 men and 9 women (median age, 58 years; range 34 to 74 years). Stage 1 was 1 patients, Stage 11, 7 patient, and Stage 111, 30 patients.
Among 33 patients who received radiotherapy with curative intent, follow up radiological study revealed complete response in 12 patients (36%), partial response, in 9 patients (27%), and minimal response, in 5 patients (15%), while 7 patients (21%) were nonresponders. Median survival for all patients was 6.9 months; squamous cell carcinoma, 7.3 months, adenocarcinoma, 5.9 months. Responders survived median 7 months, while nonresponders survived median 1.9 months.
Improved complete response rate and survival were shown in high radiation dose group. As prognostic factors, age, initial performance status, sex, histology and tumor location were evaluated.
Å°¿öµå
Nonsmal cell lung cancer, Radiotherapy, Response, Survival Prognostic factors
KMID :
0362919860040010055
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À¯È¿¼º°á°ú(Recomendation)
Responders survived median 7 months, while nonresponders survived median 1.9 months. Improved complete response rate and survival were shown in high radiation dose group.