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A Case of Herpes Simplex Virus Type 2 Encephalitis of a Newborn Delivered by a Mother without Prenatal Screening
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ÀÌÀº¼·(Lee Eun-Seob) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±èÁØ¿µ(Kim Joon-Young) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
ÀÌ°ÇÈñ(Lee Kon-Hee) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
ÀÌÁ¤¿ø(Lee Jung-Won) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
ÀÌ¿ëÁÖ(Lee Yong-Ju) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
¿À¿¬Á¤(Oh Yeon-Joung) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
¹æÁö¼®(Bang Ji-Seok) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
¼ºÅÂÁ¤(Sung Tae-Jung) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
Abstract
´Ü¼ø Æ÷Áø ¹ÙÀÌ·¯½º ³ú¿°Àº ÀûÀýÇÑ »êÀüÁø´Ü°ú °ü¸®·Î ÃÖ±Ù¿¡´Â µå¹°°Ô ¹ß»ýÇÏ°í ÀÖ´Â ÁúȯÀÌ´Ù. ´Ü¼ø Æ÷Áø ¹ÙÀÌ·¯½º ³ú¿°Àº ÁßÃ߽Űæ°è¿¡ ½É°¢ÇÑ ¿µÇâÀ» ³¢Ä¡¸ç, ƯÈ÷ ÃøµÎ¿±°ú ÀüµÎ¿±¿¡ ¿µÇâÀ» ÁØ´Ù. °í¿ë·®ÀÇ Ç×¹ÙÀÌ·¯½ºÁ¦ Á¤¸ÆÁÖ»ç Ä¡·á¸¦ Á¶±â¿¡ ½ÃÀÛÇÏ´õ¶óµµ »ýÁ¸ÀÚ¿¡¼ ½É°¢ÇÑ ÈÄÀ¯ÁõÀ» ³²±â±â ¶§¹®¿¡ ´Ü¼ø Æ÷Áø ¹ÙÀÌ·¯½ºÀÇ Á¶±â Áø´ÜÀº ¹«¾ùº¸´Ù Áß¿äÇÏ´Ù. ÀúÀÚµéÀº ÀûÀýÇÑ »êÀü°ü¸®¸¦ ¹ÞÁö ¾ÊÀº »ê¸ð¿¡¼ ÅÂ¾î³ »ýÈÄ 14ÀÏµÈ ½Å»ý¾Æ°¡ ¹ß¿°ú ¼öÀ¯°¨¼Ò·Î ÀÀ±Þ½ÇÀ» ÅëÇØ ÀÔ¿øÇÏ¿© ¹ÙÀÌ·¯½º ³ú¼ö¸·¿°ÀÌ ÀǽɵǾî ÀÔ¿ø 2º´ÀÏ° Ç×¹ÙÀÌ·¯½ºÁ¦ Á¤¸ÆÁÖ»ç Ä¡·á¸¦ ½ÃÀÛÇÏ¿´Áö¸¸, °æ·ÃÀÌ ¹ß»ýÇÏ¿´°í, ÀÌÈÄ ÁßÇÕÈ¿¼Ò¿¬¼â¹ÝÀÀ°ú ¹è¾ç°Ë»ç¸¦ ÅëÇØ Á¦ 2Çü ´Ü¼øÆ÷Áø¹ÙÀÌ·¯½º ³ú¿°À¸·Î È®ÁøµÈ ¿µ±¸ÀûÀÎ ³úÀÇ ½É°¢ÇÑ ÈÄÀ¯ÁõÀ» µ¿¹ÝÇÑ Áõ·Ê¸¦ °æÇèÇÏ¿´±â¿¡ ÀÌ¿¡ º¸°íÇÏ´Â ¹ÙÀÌ´Ù.
Neonatal herpes simplex virus (HSV) encephalitis is a rare disease nowadays because of prenatal screening test and management. It shows progressive central nervous system manifestations affecting predominantly temporal and frontal lobes. Early diagnosis of HSV encephalitis is important since even with the early initiation of high-dose intravenous acyclovir therapy, it results in serious morbidity among survivors. A 14-day-old neonate with fever and poor oral intake was admitted via emergency department. The next day she had seizures and the brain was damaged with permanent sequelae despite of early administration of intravenous acyclovir on day 2 of admission. We report a serious case of HSV encephalitis diagnosed as type 2 HSV by PCR and culture of a newborn who was delivered by a mother without proper prenatal screening test.
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´Ü¼øÆ÷Áø, ½Å»ý¾Æ, ³ú¿°
Encephalitis, Herpes Simplex, Newborn
KMID :
0361720140250030195
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