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Discrepancy between Non-stress Test Result and Umbilical Artery Doppler Study in a Pregnancy Complicated by Diabetes; A Case Report

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°íÀçȯ(Koh Jae-Whoan) - ÀÎÁ¦´ëÇб³ ÀÏ»ê¹éº´¿ø »êºÎÀΰú

Abstract

ÀӽŠÀü ´ç´¢´Â ÁÖ»ê±â »ç¸Á·üÀÇ ÁÖ¿ä À§ÇèÀÎÀÚ·Î ¾Ë·ÁÁ® ÀÖÀ¸³ª ´ç´¢°¡ ÇÕº´µÈ Àӽſ¡ ´ëÇÑ ÃÖÀûÀÇ ÅÂ¾Æ ¾È³ç Æò°¡¿¡ ´ëÇØ¼­ ¾ÆÁ÷ Á¤ÇØÁø ¹Ù°¡ ¾ø´Â ½ÇÁ¤ÀÌ´Ù. ÀúÀÚµéÀº ÀӽŠÁß ´ç´¢·Î Áø´Ü¹Þ°í ºÐ¸¸ ÈÄ ´ç´¢·Î È®ÁøµÈ 32¼¼ ÃÊ»ê¸ð¿¡¼­ ÀӽŠ32ÁÖºÎÅÍ ºñ¼öÃà°Ë»ç, ÅÂ¾Æ »ý¹°¸®ÇÐÀû°è¼ö, Á¦´ëµ¿¸Æ µµÇ÷¯ °Ë»ç¸¦ ½ÃÇàÇÏ¿´´Ù. ÀӽŠ37ÁÖ 4ÀÏ¿¡ ºñ¼öÃà°Ë»ç¿¡¼­ ¹ÝÀÀ¼ºÀ» º¸¿´À¸³ª Á¦´ëµ¿¸ÆÀÇ µµÇ÷¯ °Ë»ç¿¡¼­ È®Àå±â¸» Ç÷·ùÀÇ ¿ªÀü ¼Ò°ßÀ» º¸¿© ÀÀ±Þ Á¦¿ÕÀý°³¼ú·Î ºÐ¸¸ÇÏ¿´°í Á¦´ë µ¿¸Æ pH¼öÄ¡°¡ 7.171ÀÇ »êÇ÷ÁõÀ» º¸¿´´Ù. ´ç´¢°¡ ÇÕº´µÈ Àӽſ¡¼­ žư¨½Ã¸¦ Çϴµ¥ Á¦´ëµ¿¸Æ µµÇ÷¯ÀÇ ÀÓ»óÀû À¯¿ë¼ºÀ» º¸¿©ÁÖ´Â Áõ·Ê·Î º¸°íÇÏ´Â ¹ÙÀÌ´Ù.
Pregestational diabetes is a well-known risk factor for perinatal mortality, and regarded as an important cause of stillbirth. Unfortunately, more than half of stillbirths remain unexplained. Nevertheless, there is no consensus regarding the optimal timing and content of antepartum testing in pregnancies complicated by diabetes. A 32-year-old primigravida presented with diabetes diagnosed during pregnancy. Antenatal fetal surveillance tests including nonstress test, biophysical profile, and Doppler waveforms of umbilical arteries were performed twice weekly, beginning at 32 weeks gestation. At 37+4 weeks¡¯ gestation, a discrepancy in the surveillance test results arose when reversed end-diastolic flow in the umbilical arteries was seen, despite a reactive nonstress test. A male baby was delivered by cesarean section. The umbilical arterial pH at delivery was 7.171. Antenatal fetal surveillance in pregnancies complicated by diabetes should include evaluation of Doppler waveforms in the umbilical vessels, regardless of the presence or absence of maternal vasculopathy.

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Pregestational diabetes, Unexplained fetal demise, Antenatal fetal surveillance
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DOI
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ICD 03
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