Effect of Ultrasonography-Guided Botulinum Toxin Type A Injection in Holmes¡¯ Tremor Secondary to Pontine Hemorrhage: Case Report

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¾È¼Ò¿¬(Ahn So-Yeon) - National Rehabilitation Center Rehabilitation Hospital Department of Rehabilitation Medicine
±èµ¿¾Æ(Kim Dong-A) - National Rehabilitation Center Rehabilitation Hospital Department of Rehabilitation Medicine
¹Ú¿¬¿Á(Park Youn-Ok) - National Rehabilitation Center Division of Education & Public Relations
½ÅÁØÈ£(Shin Joon-Ho) - National Rehabilitation Center Rehabilitation Hospital Department of Rehabilitation Medicine

Abstract

Holmes¡¯ tremor is a low-frequency rest and intentional tremor secondary to various insults, including cerebral ischemia, hemorrhage, trauma, or neoplasm. Pharmacologic treatment is usually unsuccessful, and some cases require surgical intervention. We report a rare case of Holmes¡¯ tremor secondary to left pontine hemorrhage in a 29-year-old Asian male patient who developed 1.6-Hz postural and rest tremor of the right hand. He responded markedly to ultrasonography-guided botulinum toxin type A injection. To our knowledge, this is the first report of Homes¡¯ tremor treated with ultrasonography-guided botulinum toxin type A injection with favorable results.

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Tremor, Botulinum toxins, Ultrasonography
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