Central Hyperthermia Treated With Baclofen for Patient With Pontine Hemorrhage
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ÀÌÇöö(Lee Hyun-Cheol) - Konkuk University School of Medicine Department of Rehabilitation Medicine
±èÁ¾¹®(Kim Jong-Moon) - Konkuk University School of Medicine Department of Rehabilitation Medicine
ÀÓÀç±¹(Lim Jae-Kuk) - Konkuk University School of Medicine Department of Rehabilitation Medicine
±è½Å°æ(Kim Shin-Kyoung) - Konkuk University School of Medicine Department of Rehabilitation Medicine
Á¶À±½Ä(Jo Yoon-Sik) - Konkuk University School of Medicine Department of Neurology
Abstract
Central hyperthermia is a very rare disease; however, once it happens, it is associated with a poor prognosis and high mortality for patients with severe brainstem strokes. Following a pontine hemorrhage, a 46-years-old female developed prolonged hyperthermia. Work-ups to the fever gave no significant clues for the origin of fever, and hyperthermia did not respond to any empirical antibiotics or antipyretic agents. The patient¡¯s body temperature still fluctuated in a range of 37.5oC to 39.2oC. Considering the lesion of hemorrhage, we suspected central hyperthermia rather than infectious diseases. We started with baclofen administration at a dose of 30 mg/day. The body temperature changed to a range of 36.6oC to 38.2oC. We raised the dose of baclofen to 60 mg/day. The patient¡¯s body temperature finally dropped to a normal range. Central hyperthermia, caused by failures of thermoregulatory pathways in brainstem, following the pontine hemorrhage rarely occurs. Baclofen can be used to treat suspected central hyperthermia in a patient with pontine hemorrhage.
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Fever, Pons, Hemorrhage, Baclofen
KMID :
0361420140380020269
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