Impact of Exercise-Based Cardiac Rehabilitation on De Novo Coronary Lesion in Patients With Drug Eluting Stent
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ÃÖÈñÀº(Choi Hee-Eun) - Inje University Sanggye Paik Hospital Department of Rehabilitation Medicine
À̺´ÁÖ(Lee Byeong-Ju) - Inje University Sanggye Paik Hospital Department of Rehabilitation Medicine
±èö(Kim Chul) - Inje University Sanggye Paik Hospital Department of Rehabilitation Medicine
Abstract
Objective: To compare the rate of progression of de novo lesion between the cardiac rehabilitation (CR) and control groups.
Methods: This is a retrospective observational study. Patients who received drug-eluting stent (DES) due to acute coronary syndrome were included as subjects. The CR group received eight weeks of early CR program, and sustained a self-exercise program in the homes. The control group was instructed to exercise independently. Nine months after the first insertion of DES, we implemented follow-up coronary angiography, and compared the rate of progression of de novo lesion by quantitative angiographic measurement between the two groups.
Results: A total of 81 patients were recruited as subjects to CR group (n=32) or control group (n=49). At nine months, late luminal loss was 0.04¡¾0.23 mm in the CR group and 0.00¡¾0.31 mm in the control group (p=0.54, observed power=0.10). Late loss was -0.90%¡¾9.53% in the CR group and 0.80%¡¾11.15% in the control group (p=0.58, observed power=0.05). No target lesion revascularization procedures were needed in the CR group, while two in the control group (p=0.25). In the CR group, mean VO2max was significantly improved from 24.36¡¾5.00 to 27.68¡¾5.24 mL/kg/min (p<0.001).
Conclusion: We could not observe a statistically significant difference in the progression rate of de novo lesion between the CR and control groups. Thus the current amount of nine months exercise-based CR program does not seem to have a distinct impact on the retardation of de novo coronary lesion in patients who received percutaneous coronary intervention with DES.
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Coronary stenosis, Drug-eluting stents, Exercise, Rehabilitation
KMID :
0361420140380020256
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