Th e Signifi cance of Transcutaneous Continuous Overnight CO2 Monitoring in Determining Initial Mechanical Ventilator Application for Patients with Neuromuscular Disease

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À̼ø±Ô(Lee Soon-Kyu) - Yonsei University College of Medicine Department of Rehabilitation Medicine
±èµ¿Çö(Kim Dong-Hyun) - Wonkwang University School of Medicine Department of Rehabilitation Medicine
ÃÖ¿ø¾Æ(Choi Won-Ah) - Yonsei University College of Medicine Department of Rehabilitation Medicine
¿øÀ¯Èñ(Won Yu-Hui) - Yonsei University College of Medicine Department of Rehabilitation Medicine
±è¼±¹Ì(Kim Sun-Mi) - Yonsei University College of Medicine Department of Rehabilitation Medicine
°­¼º¿õ(Kang Seong-Woong) - Yonsei University College of Medicine Department of Rehabilitation Medicine

Abstract

Objective: To reveal the signifi cance of continuous transcutaneous carbon dioxide (CO2) level monitoring through reviewing cases which showed a discrepancy in CO2 levels between arterial blood gas analysis (ABGA) and continuous transcutaneous blood gas monitoring.

Method: Medical record review was conducted retrospectively of patients with neuromuscular diseases who had started home mechanical ventilation between June 2008 and May 2010. Th e 89 patients underwent ABGA at the 1st hospital day, and changes to their CO2 level were continuously monitored overnight with a transcutaneous blood gas analysis device. The number of patients who initially appeared to show normal PaCO2 through ABGA, yet displayed hypercapnea through overnight continuous monitoring, was counted.

Results: 36 patients (40.45%) presented inconsistent CO2 level results between ABGA and continuous overnight monitoring. Th e mean CO2 level of the 36 patients using ABGA was 37.23¡¾5.11 mmHg. However, the maximum and mean CO2 levels from the continuous monitoring device were 52.25¡¾6.87 mmHg and 46.16¡¾6.08 mmHg, respectively. From the total monitoring period (357.28¡¾150.12 minutes), CO2 retention over 45 mmHg was detected in 198.97 minutes (55.69%).

Conclusion: Although ABGA only reflects ventilatory status at the puncturing moment, ABGA results are commonly used to monitor ventilatory status in most clinical settings. In order to decide the starting point of home mechanical ventilation in neuromuscular patients, continuous overnight monitoring should be considered to assess latent CO2 retention.

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Respiratory failure, Blood gas analysis, Transcutaneous blood gas monitoring, Mechanical ventilation
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CO2 retention over 45 mmHg was detected in 198.97 minutes (55.69%) from the total monitoring period (357.28¡¾150.12 minutes).
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DOI
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ICD 03
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