½Ã½Å°æÀÔü»çÁøÀ¸·Î ÃøÁ¤ÇÑ ½Ã½Å°æÀ¯µÎÁÖÀ§À§Ãà ³ÐÀÌÀÇ ÀçÇö¼º°ú ³ì³»Àå¾È Áø´ÜÀÇ À¯¿ë¼º
Repeatability of Peripapillary Atrophy Parameters Measured Using Optic Disc Stereophotography and Evaluation of Its Diagnostic Ability
´ëÇѾȰúÇÐȸÁö 2014³â 55±Ç 4È£ p.570 ~ p.577
À±Àϼ®(Yun Il-Suk) - ¾ÆÁÖ´ëÇб³ ÀÇ°ú´ëÇÐ ¾È°úÇб³½Ç
À̸¶ºó(Lee Mar-Vin) - ¾ÆÁÖ´ëÇб³ ÀÇ°ú´ëÇÐ ¾È°úÇб³½Ç
Abstract
¸ñÀû: ½Ã½Å°æÀ¯µÎÁÖÀ§À§ÃàÀ» °¡Áø ȯÀÚ¿¡¼ ½Ã½Å°æÀÔü»çÁøÀ¸·Î ÃøÁ¤µÈ ½Ã½Å°æÀ¯µÎÁÖÀ§À§Ãà¸éÀû°ú °ü·Ã ÀÎÀÚµéÀÇ °³¹æ°¢³ì³»ÀåÀÇ Áø´Ü¿¡ ÀÖ¾î¼ÀÇ À¯¿ë¼ºÀ» ¾Ë¾Æº¸°íÀÚ ÇÑ´Ù.
´ë»ó°ú ¹æ¹ý: ½Ã½Å°æÀ¯µÎÁÖÀ§À§ÃàÀ» °¡Áø 65¸íÀÇ È¯ÀÚ¸¦ ´ë»óÀ¸·Î ½Ã½Å°æÀÔü»çÁø¿¡ ³»ÀåµÇ¾î ÀÖ´Â ¾Ë°í¸®µëÀ» ÀÌ¿ëÇÏ¿© ½Ã½Å°æ¸éÀû, ½Ã½Å°æÇÔ¸ô¸éÀû, ½Ã½Å°æÅ׵θ®¸éÀû, ¼öÁ÷ ½Ã½Å°æÀ¯µÎÇÔ¸ôºñ, À¯µÎÇÔ¸ô ¸éÀûºñ, ½Ã½Å°æÀ¯µÎÁÖÀ§ À§Ãà¸éÀû, º£Å¸¿µ¿ª ¸éÀû, ¾ËÆÄ¿µ¿ª ¸éÀûÀ» ±¸ÇÏ¿´´Ù. Area under receivers operating characteristic (AUROC) curve·Î ½Ã½Å°æÀ¯µÎÁÖÀ§À§Ãà ÀÎÀÚµéÀÇ ³ì³»Àå Áø´Ü·ÂÀ» ±¸ÇÏ¿´°í, ÀçÇö¼ºÀ» ¾Ë¾Æº¸±â À§ÇØ µÎ ¸íÀÇ °Ë»çÀÚ°¡ µ¿ÀÏÇÑ ½Ã½Å°æÀ¯µÎÀÔü »çÁøÀ» ºÐ¼®ÇÏ¿´´Ù.
°á°ú: ¼öÁ÷ À¯µÎÇÔ¸ôºñÀ², À¯µÎÇÔ¸ô¸éÀûºñÀ², º£Å¸¿µ¿ª ¸éÀû, ½Ã½Å°æÀ¯µÎÇÔ¸ô¿¡¼ º£Å¸¿µ¿ª¸éÀûºñÀ²°ú ¾ÈÃàÀå ±æÀÌ°¡ °³¹æ°¢³ì³»Àå ȯÀÚ¿¡¼ Á¤»ó¾È¿¡ ºñÇÏ¿© Åë°èÀûÀ¸·Î À¯ÀÇÇÏ°Ô ³ô°Ô ÃøÁ¤µÇ¾ú´Ù(p£¼0.05). ½Ã½Å°æÀ¯µÎÁÖÀ§ ¸éÀû´ç º£Å¸¿µ¿ª ¸éÀûºñ°¡ ½Ã¾ß°Ë»çÀÇ Mean deviation (MD)°ú °ÇÑ »ó°ü°ü°è¸¦ º¸¿´´Ù. ½Ã½Å°æÀ¯µÎÁÖÀ§ À§Ãà°ú °ü·ÃµÈ ÀÎÀÚµé Áß ½Ã½Å°æ ¸éÀû´ç À¯µÎÁÖÀ§À§Ãà ¸éÀûºñ (0.786)ÀÇ Áø´Ü·ÂÀÌ °¡Àå ³ô¾Ò´Ù. ½Ã½Å°æÀ¯µÎ»çÁøÀ» ÀÌ¿ëÇÏ¿© ÃøÁ¤ÇÑ ½Ã½Å°æÀ¯µÎÁÖÀ§À§Ãà ¸éÀû°ú º£Å¸¿µ¿ªÀº ÁÁÀº ÀçÇö¼º°ú ¹Ýº¹¼ºÀ» º¸¿´´Ù.
°á·Ð: ½Ã½Å°æÀ¯µÎ»çÁøÀ» ÅëÇØ ÃøÁ¤ÇÑ ½Ã½Å°æÀ¯µÎÁÖÀ§À§Ãà ÁöÇ¥µéÀº ÀçÇö¼º°ú ÀÏÄ¡µµ°¡ ¿ì¼öÇÏ¿© ³ì³»Àå ȯÀÚÀÇ °æ°ú °üÂû ½Ã ½Ã½Å°æ À¯µÎÁÖÀ§ À§ÃàÀÇ º¯È¸¦ °üÂûÇÏ´Â µ¥ À¯¿ëÇÏ°Ô ¾²ÀÏ ¼ö ÀÖÀ» °ÍÀ¸·Î »ý°¢ÇÑ´Ù.
Purpose: To investigate the measurement repeatability of peripapillary atrophy (PPA) parameters obtained by optic disc stereophotography (ODP) and evaluate the usefulness of PPA parameters to differentiate open-angle glaucoma (OAG) from normal eyes in patients with PPA.
Methods: Sixty-five eyes of 65 patients with PPA were examined. Disc area, cup area, rim area, vertical cup to disc (CD) ratio, CD area ratio, PPA area, zone beta (¥â) area and zone alpha (¥á) area were obtained by ODP using intrinsic algorithms. The area under the receivers operating characteristic (AUROC) curves was used to compare the PPA parameters with that of the disc parameters to differentiate OAG from normal eyes. Two examiners analyzed PPA parameters to confirm reproducibility and repeatability of ODP.
Results: Vertical CD ratio (VCD), area CD ratio, zone ¥â area, zone ¥â area per PPA area, zone ¥â area per disc area and axial length were significantly larger in OAG patients (p < 0.05). Among PPA parameters, zone ¥â area per PPA area was strongly correlated with MD (r = -0.431) and PSD (r = 0.411). In addition, PPA (area) to disc area ratio showed the best diagnostic ability (AUROC curve value of 0.786) when comparing the OAG group to the normal group. PPA area and zone ¥â area obtained by ODP showed good reproducibility and repeatability (ICC > 0.997).
Conclusions: The PPA measurement obtained by ODP has good reproducibility and consistency and can be a useful tool in monitoring PPA changes in glaucoma patients.
Å°¿öµå
Glaucoma, Optic disc stereophotography, Peripapillary atrophy, Reproducibility, Zone beta
KMID :
0360220140550040570
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)