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Analysis of Factors Associated with Retinal Vascular Caliber in Normal Korean Subjects

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ÀÓÁ¾Âù(Im Jong-Chan) - °æºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾È°úÇб³½Ç
½ÅÀçÇÊ(Shin Jae-Pil) - °æºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾È°úÇб³½Ç
±èÀÎÅÃ(Kim In-Taek) - °æºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾È°úÇб³½Ç
¹Úµ¿È£(Park Dong-Ho) - °æºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾È°úÇб³½Ç

Abstract

¸ñÀû: Á¤»ó Çѱ¹ÀÎÀ» ´ë»óÀ¸·Î ¸Á¸· µ¿Á¤¸ÆÀÇ Á÷°æÀ» ÃøÁ¤Çϰí, ¿¬·É¿¡ µû¸¥ ¸Á¸· Ç÷°ü Á÷°æÀÇ º¯È­¿Í ¸Á¸· Ç÷°ü Á÷°æ¿¡ ¿µÇâÀ» ¹ÌÄ¡´Â ÀÎÀÚ¿¡ ´ëÇÏ¿© ¾Ë¾Æº¸°íÀÚ ÇÑ´Ù.

´ë»ó°ú ¹æ¹ý: Á¤»óÀÎ 152¸íÀÇ ¾ÈÀú »çÁøÀ» ÃÔ¿µÇϰí, ÄÄÇ»ÅÍ ÇÁ·Î±×·¥(IVAN)À» ÀÌ¿ëÇÏ¿© central retinal artery equivalent (CRAE)¿Í central retinal vein equivalent (CRVE)¸¦ ÃøÁ¤Çϰí, ¿¬·É, ¼ºº°, °íÇ÷¾Ð, ´ç´¢, Èí¿¬°ú °°Àº °ü·Ã ÀÎÀÚ¿Í ¸Á¸· Ç÷°ü Á÷°æ°úÀÇ °ü°è¸¦ ºÐ¼®ÇÏ¿´´Ù.

°á°ú: Á¤»ó Çѱ¹ÀÎÀÇ ¸Á¸· Ç÷°ü Á÷°æÀº CRVE 209.33 ¡¾ 12.40 ¥ìm, CRAE 149.70 ¡¾ 9.01 ¥ìm·Î ÃøÁ¤µÇ¾ú°í ¿¬·ÉÀÌ Áõ°¡ÇÔ¿¡ µû¶ó CRVE¿Í CRAE´Â °¨¼ÒÇÏ¿´´Ù(p£¼0.001, respectively). CRVE¿Í CRAE´Â ³²ÀÚ°¡ ¿©ÀÚº¸´Ù À¯ÀÇÇÏ°Ô Å©°Ô ÃøÁ¤µÇ¾ú´Ù(p=0.002, p=0.042, respectively). ¿¬·É°ú ¼ºº°À» ÅëÁ¦ÇÑ ÈÄ, °íÇ÷¾Ð±ºÀÇ CRVE¿Í CRAE´Â ºñ°íÇ÷¾Ð±º¿¡ ºñÇØ À¯ÀÇÇÏ°Ô ÀÛ¾ÒÀ¸¸ç(p=0.038, p=0.032, respectively), Èí¿¬ÀÚ±º°ú ºñÈí¿¬ÀÚ±º, ´ç´¢±º°ú ºñ´ç´¢±º¿¡ ´ëÇÑ CRVE¿Í CRAEÀÇ Â÷ÀÌ´Â À¯ÀÇÇÏÁö ¾Ê¾Ò´Ù(p£¾0.05, respectively).

°á·Ð: Á¤»ó Çѱ¹ÀÎÀÇ ¸Á¸· Ç÷°ü Á÷°æÀº ¿¬·ÉÀÌ Áõ°¡ÇÔ¿¡ µû¶ó ÀÛ¾ÆÁ³´Ù. ¼ºº°°ú °íÇ÷¾ÐÀº ¸Á¸· Ç÷°ü Á÷°æ¿¡ ¿µÇâÀ» ¹ÌÄ¡´Â ÀÎÀÚÀ̸ç,
Èí¿¬°ú ´ç´¢´Â ¿µÇâÀ» ¹ÌÄ¡Áö ¾Ê¾Ò´Ù.
Purpose: To measure the diameter of the retinal arterial and venous caliber of normal Korean subjects and evaluate the factors affecting these diameters.

Methods: Fundus photography was performed on 152 normal Korean subjects. Central retinal artery equivalent (CRAE) and central retinal vein equivalent (CRVE) were measured with a computer-based program (IVAN), and were used to investigate the relationship between the diameter and factors including age, gender, hypertension, diabetes, and smoking.

Results: Among the study subjects, the CRVE was 209.33 ¡¾ 12.40 ¥ìm and the CRAE was 149.70 ¡¾ 9.01 ¥ìm. The CRVE and CRAE decreased with increasing age in all study subjects (both p < 0.001). There were significant gender differences in the CRVE and CRAE (p = 0.002, p = 0.042, respectively). After adjusting for age and gender, the hypertension group showed smaller CRVE and CRAE than the non-hypertension group (p = 0.038, p = 0.032, respectively). Smoking and diabetes were not significant factors affecting the CRAE and CRVE (both p > 0.05).

Conclusions: In our study group, retinal vascular caliber of normal Korean subjects decreased with aging. Retinal vascular caliber was affected by gender and hypertension, but not by smoking and diabetes.

Ű¿öµå

Central retinal artery equivalent, Central retinal vein equivalent, Retinal vascular caliber, Retinal vessel diameter
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ÇмúÁøÈïÀç´Ü(KCI) KoreaMed ´ëÇÑÀÇÇÐȸ ȸ¿ø 
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ÁßÀç¹æ¹ý(Intervention Type)
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DOI
KCDÄÚµå
ICD 03
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