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Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus : Comparison to B-Scan Ultrasonography

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Abstract

¸ñ Àû: ½ºÆåÆ®·³¿µ¿ª ºû°£¼·´ÜÃþÃÔ¿µ±â(spectral domain optical coherence tomography; SD-OCT)¸¦ ÀÌ¿ëÇÏ¿© ¸Æ¶ô¸· ¸ð¹ÝÀÇ Æ¯Â¡À» ¾Ë¾Æº¸°í ÃÊÀ½ÆÄ ¼Ò°ß°ú ºñ±³ÇÏ¿´´Ù.

´ë»ó ¹× ¹æ¹ý: 124¸í ¸Æ¶ô¸· ¸ð¹Ý ȯÀÚÀÇ 124¾ÈÀÇ Àǹ«±â·Ï°ú enhanced depth imaging (EDI) ¹æ¹ýÀ¸·Î ÃÔ¿µÇÑ ½ºÆåÆ®·³¿µ¿ª ºû°£¼·´Ü ÃþÃÔ¿µ ¼Ò°ß°ú ÃÊÀ½ÆÄ °Ë»ç ¼Ò°ßÀ» ÈÄÇâÀûÀ¸·Î ºñ±³ÇÏ¿´´Ù.

°á °ú: 124¾ÈÀ» ½ºÆåÆ®·³¿µ¿ª ºû°£¼·´ÜÃþÃÔ¿µ±âÀÇ EDI ¹æ¹ýÀ¸·Î ÃøÁ¤ÇÑ °á°ú 43¾È(35%)¿¡¼­ ºÐ¼®Çϱ⿡ ÁÁÀº ¿µ»ó °á°ú¸¦ ¾ò¾ú´Ù. °üÂûµÇ´Â Ư¡Àû ¼Ò°ßÀº choroidal shadowing, choriocapillary thinning°ú °°Àº ¸Æ¶ô¸·ÀÇ º¯È­°¡ 37¾È(86%), ¸Á¸·»ö¼Ò»óÇÇÀÇ º¯È­´Â 27¾È (63%), ¸Á¸·ÇϾ×Àº 9¾È(21%)À̾ú´Ù. ¸Æ¶ô¸· ¸ð¹ÝÀÇ Æò±Õ µÎ²²´Â ÃÊÀ½ÆÄ·Î ÃøÁ¤ÇßÀ» ¶§ 1295 ¥ìm (780-2400 ¥ìm), ½ºÆåÆ®·³¿µ¿ª ºû°£¼· ´ÜÃþÃÔ¿µ±â·Î ÃøÁ¤ÇßÀ» ¶§ 817 ¥ìm (120-1850 ¥ìm)¿´°í, µÎ ÃøÁ¤°ªÀÇ Æò±Õ Â÷ÀÌ´Â 475 ¥ìm (27-1319 ¥ìm)¿´´Ù(p£¼0.05).

°á ·Ð: ½ºÆåÆ®·³¿µ¿ª ºû°£¼·´ÜÃþÃÔ¿µ±â´Â ÃÊÀ½ÆÄ¿¡ ºñÇØ ¸Æ¶ô¸· ¸ð¹ÝÀÇ µÎ²²¸¦ Á¤È®ÇÏ°í ¾ã°Ô ÃøÁ¤Çϸç, ÀÌ´Â Á¾¾çÀÇ °æ°ú °üÂû°ú ´Ù¸¥ ¸Á¸· ¹× ¸Æ¶ô¸· º´º¯°úÀÇ °¨º°Áø´Ü¿¡ À¯¿ëÇÏ´Ù.
Purpose: To evaluate the characteristics of choroidal nevus using the enhanced depth imaging spectral domain optical coherence tomography (EDI SD-OCT), with a comparison to the B scan ultrasound (BUS) findings.

Methods: Medical records of 124 eyes of 124 choroidal nevus patients were reviewed retrospectively. All patients underwent fundus photography (FP), EDI SD-OCT, and BUS.

Results: Of 124 eyes with choroidal nevus examined by EDI SD-OCT, 43 eyes (35%) displayed good images to study. The most common EDI-OCT imaging features included choroidal shadowing, choriocapillary thinning, retinal pigment epithelial changes, and overlying subretinal fluid. The mean nevus thickness was 817 ¥ìm (120-1850 ¥ìm) by EDI-OCT compared 1295 ¥ìm (780-2400 ¥ìm) by BUS. The mean difference in the tumor thickness between two techniques was 475 ¥ìm (27-1319 ¥ìm) (p < 0.05).

Conclusions: These results have suggested that imaging of choroidal nevus with EDI-OCT shows superior measurement of its characteristics compared with ultrasonography. The clinical utility of this modality is emerging. EDI-OCT is useful in distinguishing suspicious nevi from other chorioretinal lesions, detecting tumor re-growth along the treatment margin, and demonstrating retinal or choroid tumor location.

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Choroidal Nevus, Enhanced Depth Imaging Optical Coherent Tomography, Ultrasonography
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