»õ·Î¿î ½Ã½Å°æ Å× ³ÊºñÀÇ ±ÔÄ¢À» ÀÌ¿ëÇÑ Á¤»ó¾È°ú ³ì³»Àå¾ÈÀÇ ±¸º°
Discriminating Between Normal and Glaucomatous Eyes Using the Modified ISNT Rule
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ÀÌ¸í¿ø(Lee Myung-Won) - ´Ü±¹´ëÇб³ Àǰú´ëÇÐ ¾È°úÇб³½Ç
½ÅÁ¾ÈÆ(Shin Jong-Hoon) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾È°úÇб³½Ç
±ââ¿ø(Kee Chang-Won) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼º¼¿ïº´¿ø ¾È°úÇб³½Ç
Abstract
¸ñÀû: Á¤»ó¾È°ú ³ì³»Àå¾ÈÀ» ´ë»óÀ¸·Î ±âÁ¸ÀÇ ½Ã½Å°æ Å× ³Êºñ¿¡ °üÇÑ ±ÔÄ¢(ISNT rule, ½Ã½Å°æ Å× ³Êºñ°¡ ÇÏÃø£¾»óÃø£¾ºñÃø£¾ÀÌÃø)°ú ºñ ±³ÇÏ¿© »õ·Î¿î ISNT rule (ÇÏÃø°ú »óÃø ½Ã½Å°æ Å× ³Êºñ Áß ÀÛÀº °Í£¾ºñÃø°ú ÀÌÃø ½Ã½Å°æ Å× ³Êºñ Áß Å« °Í)ÀÇ Áø´ÜÀû À¯¿ë¼º¿¡ ´ëÇØ ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.
´ë»ó°ú ¹æ¹ý: 113¸í 113¾ÈÀÇ Á¤»óÀΰú 108¸í 108¾ÈÀÇ Ãʱâ, Á߱⠳쳻Àå ȯÀÚµéÀ» ´ë»óÀ¸·Î ÇÏ¿© ÀÔü ½Ã½Å°æ»çÁøÀ» ÃÔ¿µÇÏ¿´´Ù. ÀÔü ½Ã½Å°æ»çÁøÀ» ÅëÇØ À¯µÎÇÔ¸ô °æ°è¸¦ Á¤ÇÑ ÈÄ 3, 6, 9, 12½Ã ¹æÇâÀÇ ½Ã½Å°æ Å×ÀÇ ³Êºñ¸¦ ÃøÁ¤ÇÏ¿´´Ù. ±× °á°ú¸¦ ÀÌ¿ëÇÏ¿© ±âÁ¸ÀÇ ISNT rule°ú »õ·Î¿î ISNT ruleÀÇ Á¤»ó¾È°ú ³ì³»Àå¾È Áø´Ü Á¤È®µµ¸¦ ºñ±³ÇÏ¿´´Ù.
°á°ú: 113¾ÈÀÇ Á¤»ó¾È Áß ±âÁ¸ÀÇ ISNT rule·Î Á¤»ó ÆÇÁ¤µÈ °æ¿ì´Â 58¾È(51.3%)ÀÌ¸ç »õ·Î¿î ISNT rule·Î Á¤»ó ÆÇÁ¤µÈ °æ¿ì´Â 98¾È (94.2%)À̸ç 108¾ÈÀÇ ³ì³»Àå¾È Áß ±âÁ¸ÀÇ ISNT rule·Î ³ì³»Àå ÆÇÁ¤µÈ °æ¿ì´Â 104¾È(96.3%), »õ·Î¿î ISNT rule·Î ³ì³»Àå ÆÇÁ¤µÈ °æ¿ì´Â 102¾È(94.4%)À̾ú´Ù. Cohen¡¯s Kappa analysis¸¦ ÅëÇØ µÎ Áø´Ü¹ýÀÇ Á¤È®µµ¸¦ ºñ±³Çغ» °á°ú »õ·Î¿î ISNT ruleÀÌ ±âÁ¸ÀÇ ISNT ruleº¸´Ù À¯ÀÇÇÏ°Ô ³ô¾Ò´Ù(k=0.8102, 0.4713, p£¼0.001).
°á·Ð: ±âÁ¸ÀÇ ISNT rule¿¡ ºñÇØ »õ·Î¿î ISNT ruleÀº Á¤»ó¾È ¹× ³ì³»Àå¾ÈÀÇ Áø´Ü¿¡ À¯¿ëÇϸç ÀÓ»ó¿¡¼µµ ¼Õ½±°Ô »ç¿ëÇÒ ¼ö ÀÖ´Â ¹æ¹ýÀÌ´Ù.
Purpose: To evaluate the diagnostic ability of the modified ISNT rule (disc rim thickness of the smaller of inferior and superior > the larger of nasal and temporal) for normal and glaucomatous eyes compared to the classic ISNT rule (disc rim thickness of inferior > superior > nasal > temporal).
Methods: Color stereo optic disc photographs of 113 normal subjects and 108 open angle glaucoma patients with early and moderate stage were morphometrically evaluated. The classic ISNT rule and the modified ISNT rule were assessed by masked evaluation of disc photographs at the 3, 6, 9 and 12 o¡¯clock positions.
Results: Among normal subjects, 58 of 113 eyes (51.3%) were normal and in open angle glaucoma patients, 104 of 108 eyes (96.3%) were abnormal with the classic ISNT rule. Among normal subjects, 98 of 113 eyes (94.2%) were normal and in open angle glaucoma patients, 102 of 108 eyes (94.4%) were abnormal with the modified ISNT rule. The modified ISNT rule was more accurate than the classic ISNT rule in terms of Cohen¡¯s Kappa analysis used for discriminating between normal and glaucomatous eyes.
Conclusions: The modified ISNT rule is useful for differentiating between normal and glaucomatous optic nerves and easily applied in clinical practice.
Ű¿öµå
ISNT rule, Neuroretinal rim, Optic cup, Optic disc, Stereoscopic disc photography
KMID :
0360220140550010093
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