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Utility of the Noncontact Specular Microscopy for Measurements of Central Corneal Thickness

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¾ç¿µ¼º(Yang Young-Seong) - Á¶¼±´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾È°úÇб³½Ç
°íÀç¿õ(Koh Jae-Woong) - Á¶¼±´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾È°úÇб³½Ç

Abstract

¸ñÀû: ºñÁ¢Ã˰æ¸éÇö¹Ì°æÀ¸·Î ÃøÁ¤ÇÑ Á߽ɰ¢¸·µÎ²²¸¦ Àü¾ÈºÎ ºû°£¼·´ÜÃþÃÔ¿µ°è¿Í ÃÊÀ½ÆÄ °¢¸·µÎ²²ÃøÁ¤°è¸¦ ÀÌ¿ëÇÑ ÃøÁ¤°ª°ú ºñ±³ÇÏ¿© À¯¿ë¼ºÀ» ¾Ë¾Æº¸°íÀÚ ÇÑ´Ù.

´ë»ó°ú ¹æ¹ý: Á¤»óÀÎ 50¸í 50¾ÈÀ» ´ë»óÀ¸·Î µ¿ÀÏÇÑ °Ë»çÀÚ¿¡ ÀÇÇØ ºñÁ¢Ã˰æ¸éÇö¹Ì°æ, Àü¾ÈºÎ ºû°£¼·´ÜÃþÃÔ¿µ°è ±×¸®°í ÃÊÀ½ÆÄ °¢¸·µÎ ²²ÃøÁ¤°è¸¦ ÀÌ¿ëÇÏ¿© ÃøÁ¤µÈ Á߽ɰ¢¸·µÎ²²¸¦ ºñ±³ÇÏ°í °¢°¢ÀÇ »ó°ü°ü°è¸¦ ¾Ë¾Æº¸¾Ò´Ù.

°á°ú: ºñÁ¢Ã˰æ¸éÇö¹Ì°æÀ» ÀÌ¿ëÇÏ¿© ÃøÁ¤ÇÑ Á߽ɰ¢¸·µÎ²²ÀÇ Æò±Õ°ªÀº 546.92 ¡¾ 32.06 ¥ìm¿´°í, Àü¾ÈºÎ ºû°£¼·´ÜÃþÃÔ¿µ°è´Â 535.24 ¡¾ 30.54 ¥ìm, ÃÊÀ½ÆÄ °¢¸·µÎ²²ÃøÁ¤°è´Â 546.38 ¡¾ 30.70 ¥ìm¿´´Ù. ºñÁ¢Ã˰æ¸éÇö¹Ì°æ°ú ÃÊÀ½ÆÄ °¢¸·µÎ²²ÃøÁ¤°è¸¦ ÀÌ¿ëÇÑ ÃøÁ¤Ä¡°¡ Àü¾ÈºÎ ºû°£¼·´ÜÃþÃÔ¿µ°è¸¦ ÀÌ¿ëÇÑ ÃøÁ¤Ä¡º¸´Ù À¯ÀÇÇÏ°Ô µÎ²®°Ô ÃøÁ¤µÇ¾úÀ¸³ª(p£¼0.001, p£¼0.001) ºñÁ¢Ã˰æ¸éÇö¹Ì°æ°ú ÃÊÀ½ÆÄ °¢¸· µÎ²²ÃøÁ¤°è¸¦ ÀÌ¿ëÇÑ ÃøÁ¤Ä¡ °£¿¡´Â Åë°èÀûÀ¸·Î À¯ÀÇÇÑ Â÷À̰¡ ¾ø¾ú´Ù(p=0.505). ¼¼ °Ë»ç±â±â¿¡¼­ ³ôÀº »ó°ü°ü°è¸¦ º¸¿´´Ù(r£¾0.900 in all groups, p£¼0.001 in all groups).

°á·Ð: Á¤»ó¾È¿¡¼­ ºñÁ¢Ã˰æ¸éÇö¹Ì°æ·Î ÃøÁ¤ÇÑ Á߽ɰ¢¸·µÎ²²°¡ Àü¾ÈºÎ ºû°£¼·´ÜÃþÃÔ¿µ°è¸¦ ÀÌ¿ëÇÑ °æ¿ìº¸´Ù ÃÊÀ½ÆÄ °¢¸·µÎ²²ÃøÁ¤°è·Î ÃøÁ¤ÇÑ °ª¿¡ Á»´õ À¯»çÇÑ °ªÀ» ³ªÅ¸³Â´Ù. Á¤»ó¾ÈÀÇ Á߽ɰ¢¸·µÎ²² ÃøÁ¤¿¡ ºñÁ¢Ã˰æ¸éÇö¹Ì°æÀÌ Àü¾ÈºÎ ºû°£¼·´ÜÃþÃÔÃÔ¿µ°èº¸´Ù ÃÊÀ½ÆÄ °¢¸·µÎ²²ÃøÁ¤°è¸¦ ´ëüÇÒ ¼ö ÀÖ´Â Á»´õ À¯¿ëÇÑ ¹æ¹ýÀ̶ó »ý°¢µÈ´Ù.
Purpose: To evaluate the efficacy of noncontact specular microscopy (NCSM) by comparing the measurement of central corneal thickness (CCT) to the measurement with anterior segment optical coherence tomography (AS-OCT) and ultrasound pachymetry (USP).

Methods: One examiner measured the CCT of 50 eyes of 50 healthy young subjects using NCSM, AS-OCT, and USP. The mean values and correlations were analyzed.

Results: The mean CCT value was 546.92 ¡¾ 32.06 ¥ìm with NCSM, 535.24 ¡¾ 30.54 ¥ìm with AS-OCT, and 546.38 ¡¾ 30.70 ¥ìm with USP. The CCT measurements with NCSM and USP were significantly thicker than with AS-OCT (p < 0.001, p < 0.001, respectively). There were no significant differences between the measurements obtained with NCSM and USP (p = 0.505). The 3 instruments were significantly correlated (r > 0.900 in all groups, p < 0.001 in all groups).

Conclusions: CCT measurements of healthy eyes using NCSM are more correlated with USP than AS-OCT. The CCT measurement using NCSM is a better alternative for USP than AS-OCT.

Ű¿öµå

Anterior segment optical coherence tomography, Central corneal thickness, Noncontact specular microscopy, Ultrasound pachymetry
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