Serum calcium and phosphorus levels in patients undergoing maintenance hemodialysis: A multicentre study in Korea
´ëÇѽÅÀåÇÐȸÁö 2014³â 33±Ç 1È£ p.52 ~ p.57
±è±ÙÈ£(Kim Gheun-Ho) - Hanyang University College of Medicine Department of Internal Medicine
ÃÖ¹ü¼ø(Choi Bum-Soon) - Catholic University College of Medicine Department of Internal Medicine
Â÷´ë·æ(Cha Dae-Ryong) - Korea University Medical College Department of Nephrology
Áöµ¿Çö(Chee Dong-Hyun) - Korea AbbVie Ltd.
ȲÀº¾Æ(Hwang Eun-Ah) - Keimyung University School of Medicine Department of Internal Medicine
±èÇü¿í(Kim Hyung-Wook) - Catholic University College of Medicine St. Vincent¡¯s Hospital Department of Internal Medicine
ÀåÁ¦Çö(Chang Jae-Hyun) - Gachon University of Medicine and Science Department of Internal Medicine
±èÁß°æ(Kim Joong-Kyung) - Bongseng Memorial Hospital Department of Internal Medicine
³ëÁ¤¿ì(Noh Jung-Woo) - Hallym University College of Medicine Department of Internal Medicine
Áֱǿí(Joo Kwon-Wook) - Seoul National University College of Medicine Department of Internal Medicine
ÀÌ»óö(Lee Sang-Cheol) - Good Morning Hospital Department of Internal Medicine
ÇÑ»ó¿õ(Han Sang-Woong) - Hanyang University Guri Hospital Department of Internal Medicine
±è¼¼Áß(Kim Se-Joong) - Seoul National University College of Medicine Seoul National University Bundang Hospital Department of Internal Medicine
±è¼ö¿Ï(Kim Soo-Wan) - Chonnam National University Medical School Department of Internal Medicine
½Å¼®±Õ(Shin Sug-Kyun) - National Health Insurance Service Ilsan Hospital Department of Internal Medicine
¹Ú¿øµµ(Park Won-Do) - Inje University College of Medicine Sanggye Paik Hospital Department of Internal Medicine
±è¿ø(Kim Won) - Jeonbuk National University Medical School Department of Internal Medicine
Çã¿ì¼º(Huh Woo-Seong) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Internal Medicine
±Ç¿µÁÖ(Kwon Young-Joo) - Korea University Guro Hospital College of Medicine Division of Nephrology
°¿µ¼±(Kang Young-Sun) - Korea University Medical College Department of Nephrology
Abstract
Background: In many countries, nephrologists follow clinical practice guidelines for mineral bone disorders to control secondary hyperparathyroidism (SHPT) associated with abnormal serum calcium (Ca) and phosphorus (P) levels in patients undergoing maintenance hemodialysis (MHD). The Kidney Disease Outcomes Quality Initiative (KDOQI) Guidelines have long been used in Korea, and this study was undertaken to investigate the current status of serum Ca and P control in MHD patients.
Methods: Data were collected from a total of 1,018 patients undergoing MHD without intercurrent illness, in 17 hemodialysiscenters throughout the country. Serum levels of Ca, P, and intact parathyroid hormone (iPTH) were measured over 1 year, and the average values were retrospectively analyzed.
Results: Serum levels of Ca, P, and the CaP product were 9.170.7mg/dL, 5.37 1.4mg/dL, and 48.0713.6mg2/dL2, respectively. However, the percentages of patients with Ca, P, and Ca P product levels within the KDOQI guideline ranges were 58.7%, 51.0%, and 70.7%, respectively. Of the 1,018 patients, 270 (26.5%) had iPTH 4300pg/mL (uncontrolled SHPT), whereas 435 patients (42.7%) showed iPTH o150pg/mL. Patients with uncontrolled SHPT had signi?cantly higher values of serum Ca, P, and CaP product than those with iPTH r300pg/mL.
Å°¿öµå
Calcium, Hemodialysis, Intact parathyroidhormone, Phosphorus, Secondary hyperparathyroidism
KMID :
0359920140330010052
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)