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Steroid Responsive Recurrent Limbic Encephalitis Associated With LGI1 Antibodies
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³ë°æÇÏ(Noh Kyung-Ha) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾ç»êºÎ»ê´ëÇб³º´¿ø ½Å°æ°ú
±è½ÂÁÖ(Kim Seung-Joo) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾ç»êºÎ»ê´ëÇб³º´¿ø ½Å°æ°ú
Á¶Àç¿í(Cho Jae-Wook) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾ç»êºÎ»ê´ëÇб³º´¿ø ½Å°æ°ú
½ÅÁøÈ«(Shin Jin-Hong) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾ç»êºÎ»ê´ëÇб³º´¿ø ½Å°æ°ú
ÀÌÀçÇõ(Lee Jae-Hyeok) - ºÎ»ê´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¾ç»êºÎ»ê´ëÇб³º´¿ø ½Å°æ°ú
Abstract
Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histological evidence of mesial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI1) is the autoantigen associated with limbic encephalitis that was previously attributed to voltage-gated potassium channels. We report herein a 54-year-old female with LGI1-related limbic encephalitis who presented with recurrent episodes of episodic memory impairment, depressive mood, and phantosmia. Her symptoms dramatically improved with steroid therapy.
Å°¿öµå
LGI1 encephalitis, Limbic encephalitis
KMID :
0359720140320020091
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