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Asymptomatic Rheumatoid Meningoencephalitis Presented After Discontinuation of Methotrexate
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ÀÌ°ÇÈ£(Lee Gun-Ho) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
¼Õ½Â³²(Son Seung-Nam) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
°Èñ¿µ(Kang Hee-Young) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
¹Ú±âÁ¾(Park Ki-Jong) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
ÃÖ³«Ãµ(Choi Nack-Cheon) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
ÀÓº´ÈÆ(Lim Byeong-Hoon) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
±Ç¿À¿µ(Kwon Oh-Young) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
±è¼ö°æ(Kim Soo-Kyoung) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
Abstract
Rheumatoid meningoencephalitis is a rare, but severe complication of rheumatoid arthritis (RA). A 64-year-old woman with the history of RA presented with abnormal behaviors and memory impairments since stopping methotrexate due to asymptomatic meningitis before 1 month. Brain MRI still demonstrated leptomeningeal enhancement in right fronto-temporal area, compared with the previous. Brain biopsy revealed multiple yellowish suppurative streaks in dura, and microscopically lymphoplasmic infiltrations and fibroid necrosis surrounded by granuloma. Soon after beginning treatment with corticosteroid and methotrexate, her symptoms improved.
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Meningoencephalitis, Rheumatoid arthritis, Methotrexate
KMID :
0359720140320010038
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