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Paraneoplastic Necrotizing Myopathy Associated With Ovarian Adenocarcinoma

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ÀÌÇý¹Ì(Lee Hye-Mi) - °í·Á´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
±èÁö¼±(Kim Ji-Sun) - °í·Á´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
±è¹ÎÁ÷(Kim Min-Jik) - °í·Á´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
°­¼ºÈÆ(Kang Sung-Hoon) - °í·Á´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
È«ÁøÈ­(Hong Jin-Hwa) - °í·Á´ëÇб³ Àǰú´ëÇÐ »êºÎÀΰúÇб³½Ç
¹Ú¼ºÇý(Park Sung-Hye) - °í·Á´ëÇб³ Àǰú´ëÇÐ º´¸®Çб³½Ç
±èÁöÇö(Kim Ji-Hyun) - °í·Á´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç

Abstract

We describe here a case of female patient who presented with mild proximal weakness, myalgia, and markedly elevated CPK, which could be ascribed to paraneoplastic necrotizing myopathy in association with ovarian adenocarcinoma. A histologic examination of the vastus lateralis muscle showed necrosis of muscle fibers without inflammatory cell infiltration. Her neurologic symptoms improved following tumor resection and systemic chemotherapy. Paraneoplastic necrotizing myopathy may be a presenting manifestation of malignancy, and early recognition and prompt treatment are crucial for the clinical improvement.

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Paraneoplastic myopathy, Necrotizing myopathy, Ovarian adenocarcinoma
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DOI
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ICD 03
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