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Anti-LGI1 Antibody Autoimmune Encephalitis Which Manifests Faciobrachial Dystonic Seizure

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±èÇöÁø(Kim Hyun-Jin) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
±èº¸¹Ì(Kim Bo-Mi) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
ȲÁöÇý(Hwang Ji-Hye) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
ÀÌÀ¯Áø(Lee Yoo-Jin) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
À̼øÅÂ(Lee Soon-Tae) - ¼­¿ï´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç
°­Áß±¸(Kang Joong-Koo) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ½Å°æ°úÇб³½Ç

Abstract

Anti-LGI1 (leucine-rich glioma inactivated-1) antibody encephalitis is one of autoimmune encephalitis. We report a 66-year-old man who presented with frequent, brief dystonic seizures which involve predominantly ipsilateral face and arm without cognitive impairment. Brain MRI showed normal finding. Serum and CSF tests revealed anti-LGI1 antibody. His symptom was not relieved by antiepileptic drugs, but completely controlled after immunotherapy. This case indicates that recognition of the brief, dystonic seizures should do tests for anti-LGI1 antibodies.

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Autoimmune encephalitis, LGI1, Voltage gated potassium channel
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