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A case of unrecognized pregnancy during chemotherapy in non-small cell lung cancer patient

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¹ÚÁöÀ±(Park Jee-Yoon) - ¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
¹ÚÁ¤¿ì(Park Jeong-Woo) - ¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
À̵¿¿Á(Lee Dong-Ok) - ±¹¸³¾Ï¼¾ÅÍ Àڱþϼ¾ÅÍ
¹ÚÂù¿í(Park Chan-Wook) - ¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
¹ÚÁß½Å(Park Joong-Shin) - ¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
ÀüÁ¾°ü(Jun Jong-Kwan) - ¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
½ÅÈñö(Syn Hee-Chul) - ¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç

Abstract

´ëºÎºÐÀÇ Ç×¾ÏÈ­Çпä¹ýÀº Àӽźο¡°Ô »ç¿ëµÇ¾úÀ» ¶§ À¯ÀÇÇÑ ±âÇü ¹ß»ý °¡´É¼ºÀÌ ÀÖ´Â °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. ºñ·Ï ÀϺΠÇ׾ϾàÁ¦ÀÇ °æ¿ì ±â°ü ¹ß»ý½Ã±â¸¦ Áö³ª°í Åõ¿©ÇÏ¿´À» ¶§ žƿ¡°Ô ¾ÈÀüÇÏ´Ù´Â ¿¬±¸°á°ú°¡ º¸°íµÇ°í ÀÖÀ¸³ª, ¿©ÀüÈ÷ ÀÓ½ÅÁßÀÇ ¾ÏȯÀÚ¿¡°Ô Ç×¾ÏÈ­Çпä¹ýÀ» ½ÃÇàÇÏ´Â °Í¿¡´Â ³í¶õÀÌ ÀÖÀ¸¸ç, µ¿¹°½ÇÇèÀÌ ¾Æ´Ñ »ç¶÷¿¡°Ô Ç×¾ÏÈ­Çпä¹ýÀÇ ¿µÇâÀ» ¾Ë¾Æº¼ ¼ö ÀÖ´Â ¿¬±¸¸¦ ÇÏ´Â °ÍÀº ÇÑ°è°¡ ÀÖ´Ù. ÀúÀÚµéÀº Æó¾ÏÀ» Áø´Ü¹Þ¾Æ ¿À·£ ±â°£ Áö¼ÓÀûÀ¸·Î ´Ù¾çÇÑ Ç×¾ÏÈ­Çпä¹ýÀ¸·Î Ä¡·áÇØ¿À´ø Áß ¸¸»èÀ¸·Î ÃßÁ¤µÇ´Â ½Ã±â¿¡ ÀӽŠ»ç½ÇÀ» ¾Ë°Ô µÈ ȯÀÚ 1¿¹¸¦ °æÇèÇÏ¿´±â¿¡ ¹®Çå °íÂû°ú ÇÔ²² º¸°íÇÏ´Â ¹ÙÀÌ´Ù. ȯÀÚ´Â 25¼¼ÀÇ Ãâ»ê·ÂÀÌ ¾ø´Â ¿©¼ºÀ¸·Î 6³â Àü¿¡ ºñ¼Ò¼¼Æ÷Æó¾ÏÀ» Áø´Ü¹Þ¾ÒÀ¸¸ç, ÀӽŠ»ç½ÇÀ» ¸ð¸¥ ä ÀӽŠ1, 2 »ïºÐ±â¿¡ ÇØ´çÇÏ´Â ½Ã±â¿¡µµ Áö¼ÓÀûÀ¸·Î ±ÙÄ¡Àû Ç×¾ÏÈ­Çпä¹ýÀ» ¹Þ¾ÒÀ¸³ª, ¸¶Áö¸· ¿ù°æÀϷκÎÅÍ ¾à 41ÁÖ°¡ µÇ¾úÀ» ¶§ ÀӽŻç½ÇÀ» È®ÀÎÇÏ¿´À¸¸ç, Áö¿¬ÀÓ½ÅÀ¸·Î ÀÔ¿øÇÏ¿© »êºÎÀΰú ¹× Á¾¾ç³»°ú ÇùÁøÇÏ¿¡ À¯µµºÐ¸¸ÀÌ °áÁ¤µÇ¾ú´Ù. ÀÚ¿¬ºÐ¸¸À¸·Î 2,450 gÀÇ ¿©¾Æ¸¦ Ưº°ÇÑ ÇÕº´Áõ ¾øÀÌ Ãâ»êÇÏ¿´À¸¸ç, ¾Æ±â¿¡°Ô¼­ À°¾ÈÀû ±âÇüÀº ¹ß°ßµÇÁö ¾Ê¾Ò´Ù.
Most chemotherapeutic drugs are known to possess significant teratogenic effects. Although several agents have been proven to be safe for the fetus after organogenesis period, there is limited information on their use during pregnancy and it is very difficult to establish researches on the effect to human. We report a very unique case of unrecognized pregnancy in lung cancer patient who had been treated with variable agents of chemotherapy. A 25-year-old woman (gravida 0) who had been diagnosed as non-small cell lung cancer 6 years ago and received multiple regimens of chemotherapy presented at full term pregnancy with unknown gestational period. Without knowledge of pregnancy, she received a palliative chemotherapy with Docetaxel during first and second trimesters. Vaginal delivery with induction of labor due to postterm pregnancy was performed after evaluation of her medical condition and fetal surveillance. A 2,450 g female newborn was delivered with no evidence of congenital malformations.

Å°¿öµå

ÀÓ½Å, Æó¾Ï, Ç×¾ÏÈ­Çпä¹ý
Pregnancy, Lung neoplasmas, Antineoplastic combined chemotherapy protocols
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
ÇмúÁøÈïÀç´Ü(KCI) KoreaMed ´ëÇÑÀÇÇÐȸ ȸ¿ø 
ÁÖÁ¦ÄÚµå
ÁÖÁ¦¸í(Target field)
¿¬±¸´ë»ó(Population)
¿¬±¸Âü¿©(Sample size)
´ë»ó¼ºº°(Gender)
Áúº´Æ¯¼º(Condition Category)
¿¬±¸È¯°æ(Setting)
¿¬±¸¼³°è(Study Design)
¿¬±¸±â°£(Period)
ÁßÀç¹æ¹ý(Intervention Type)
ÁßÀç¸íĪ(Intervention Name)
Å°¿öµå(Keyword)
À¯È¿¼º°á°ú(Recomendation)
A newborn was delivered with no evidence of congenital malformations.
¿¬±¸ºñÁö¿ø(Fund Source)
±Ù°Å¼öÁØÆò°¡(Evidence Hierarchy)
ÃâÆdz⵵(Year)
Âü¿©ÀúÀÚ¼ö(Authors)
´ëÇ¥ÀúÀÚ
DOI
KCDÄÚµå
ICD 03
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