Randomized trial of subfascial infusion of ropivacaine for early recovery in laparoscopic colorectal cancer surgery
Korean Journal of Anesthesiology 2016³â 69±Ç 6È£ p.604 ~ p.613
ÀÌ»óÇö(Lee Sang-Hyun) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
½É¿ì¼®(Sim Woo-Seog) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
±è°íÀº(Kim Go-Eun) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
±èÈñö(Kim Hee-Cheol) - Sungkyunkwan University School of Medicine Samsung Medical Center Division of Colorectal Surgery
ÀüÁÖÇö(Jun Joo-Hyun) - Hallym University College of Medicine Kangnam Sacred Heart Hospital Department of Anesthesiology and Pain Medicine
ÀÌÁø¿µ(Lee Jin-Young) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
½Åº´¼·(Shin Byung-Seop) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
À¯ÈñÁø(Yoo Hee-Jin) - Samsung Medical Center Biostatistics and Clinical Epidemiology Center
(Jung Sin-Ho) - Samsung Medical Center Biostatistics and Clinical Epidemiology Center
±èÁ¤¿¬(Kim Joung-Youn) - Chungbuk National University Department of Information Statistics
À̽ÂÇö(Lee Seung-Hyeon) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
(Yo Deok-Kyu) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
(Na Yu-Ri) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
Abstract
Background : There is a need for investigating the analgesic method as part of early recovery after surgery tailored for laparoscopic colorectal cancer (LCRC) surgery. In this randomized trial, we aimed to investigate the analgesic efficacy of an inverse ¡®v¡¯ shaped bilateral, subfascial ropivacaine continuous infusion in LCRC surgery.
Methods : Forty two patients undergoing elective LCRC surgery were randomly allocated to one of two groups to receive either 0.5% ropivacaine continuous infusion at the subfascial plane (n = 20, R group) or fentanyl intravenous patient controlled analgesia (IV PCA) (n = 22, F group) for postoperative 72 hours. The primary endpoint was the visual analogue scores (VAS) when coughing at postoperative 24 hours. Secondary end points were the VAS at 1, 6, 48, and 72 hours, time to first flatus, time to first rescue meperidine requirement, rescue meperidine consumption, length of hospital stay, postoperative nausea and vomiting, sedation, hypotension, dizziness, headache, and wound complications.
Results : The VAS at rest and when coughing were similar between the groups throughout the study. The time to first gas passage and time to first rescue meperidine at ward were significantly shorter in the R group compared to the F group (P = 0.010). Rescue meperidine was administered less in the R group; however, without statistical significance. Other study parameters were not different between the groups.
Conclusions : Ropivacaine continuous infusion with an inverse ¡®v ¡¯ shaped bilateral, subfascial catheter placement showed significantly enhanced bowel recovery and analgesic efficacy was not different from IV PCA in LCRC surgery.
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Analgesia, Colorectal surgery, Laparoscopy, Local anesthetics, Ropivacaine, Subfascia
KMID :
0356920160690060604
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Subfascial infusion of ropivacaine analgesic efficacy was not different from IV PCA in laparoscopic colorectal cancer (LCRC) surgery; Ropivacaine continuous infusion with an inverse ¡°v¡± shaped bilateral, subfascial catheter placement showed significantly enhanced bowel recovery.