Comparison of respiratory mechanics between sevoflurane and propofol-remifentanil anesthesia for laparoscopic colectomy
Korean Journal of Anesthesiology 2014³â 66±Ç 2È£ p.131 ~ p.135
¹æ½Ã¶ó(Bang Si-Ra) - Inje University School of Medicine Haeundae Paik Hospital Department of Anesthesiology and Pain Medicine
ÀÌ»óÀº(Lee Sang-Eun) - Inje University School of Medicine Haeundae Paik Hospital Department of Anesthesiology and Pain Medicine
¾ÈÇöÁÖ(Ahn Hyun-Joo) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
±èÁö¾Ö(Kim Jie-Ae) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
½Åº´¼·(Shin Byung-Seop) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
·ÎÈñÁø(Roe Hee-Jin) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
½É¿ì¼®(Sim Woo-Seog) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Anesthesiology and Pain Medicine
Abstract
Background: The creation of pneumoperitoneum and Trendelenburg positioning during laparoscopic surgery are associated with respiratory changes. We aimed to compare respiratory mechanics while using intravenous propofol and remifentanil vs. sevoflurane during laparoscopic colectomy.
Methods: Sixty patients undergoing laparoscopic colectomy were randomly allocated to one of the two groups: group PR (propofol-remifentanil group; n = 30), and group S (sevoflurane group; n = 30). Peak inspiratory pressure (PIP), dynamic lung compliance (Cdyn), and respiratory resistance (Rrs) values at five different time points: 5 minutes after induction of anesthesia (supine position, T1), 3 minutes after pneumoperitoneum (lithotomy position, T2), 3 minutes after pneumoperitoneum while in the lithotomy-Trendelenburg position (T3), 30 minutes after pneumoperitoneum (T4), and 3 minutes after deflation of pneumoperitoneum (T5).
Results: In both groups, there were significant increases in PIP and Rrs while Cdyn decreased at times T2, T3, and T4 compared to T1 (P < 0.001). The Rrs of group PR for T2, T3, and T4 were significantly higher than those measured in group S for the corresponding time points (P < 0.05).
Conclusions: Respiratory mechanics can be adversely affected during laparoscopic colectomy. Respiratory resistance was significantly higher during propofol-remifentanil anesthesia than sevoflurane anesthesia.
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Laparoscopy, Propofol, Remifentanil, Respiratory mechanics, Sevoflurane
KMID :
0356920140660020131
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