이종학(Lee Jong-Hak) - Kyungpook National University School of Medicine Department of Internal Medicine
박순희(Park Sun-Hee) - Kyungpook National University Hospital Department of Internal Medicine
임정훈(Lim Jeong-Hoon) - Kyungpook National University School of Medicine Department of Internal Medicine
박영재(Park Young-Jae) - Kyungpook National University School of Medicine Department of Internal Medicine
김상운(Kim Sang-Un) - Kyungpook National University School of Medicine Department of Internal Medicine
이경희(Lee Kyung-Hee) - Kyungpook National University School of Medicine Department of Internal Medicine
김경훈(Kim Kyung-Hoon) - Kyungpook National University School of Medicine Department of Internal Medicine
박승찬(Park Seung-Chan) - Kyungpook National University School of Medicine Department of Internal Medicine
정희연(Jung Hee-Yeon) - Kyungpook National University School of Medicine Department of Internal Medicine
(Kwon Owen) - Kyungpook National University School of Medicine Department of Internal Medicine
최지영(Choi Ji-Young) - Kyungpook National University School of Medicine Department of Internal Medicine
조장희(Cho Jang-Hee) - Kyungpook National University School of Medicine Department of Internal Medicine
김찬덕(Kim Chan-Duck) - Kyungpook National University School of Medicine Department of Internal Medicine
김용림(Kim Yong-Lim) - Kyungpook National University School of Medicine Department of Internal Medicine
Abstract
Background/Aims: This study analyzed the risk factors for technique survival in dialysis patients and compared technique survival rates between hemodialysis (HD) and peritoneal dialysis (PD) in a prospective cohort of Korean patients.
Methods: A total of 1,042 patients undergoing dialysis from September 2008 to June 2011 were analyzed. The dialysis modality was defined as that used 90 days after commencing dialysis. Technique survival was compared between the two dialysis modalities, and the predictive risk factors were evaluated.
Results: The dialysis modality was an independent risk factor predictive of technique survival. PD had a higher risk for technique failure than HD (hazard ratio [HR], 10.8; 95% confidence interval [CI], 1.9 to 62.0; p = 0.008) during a median follow-up of 11.0 months. In the PD group, a high body mass index (BMI) was an independent risk factor for technique failure (HR, 1.3; 95% CI, 1.0 to 1.8; p = 0.036). Peritonitis was the most common cause of PD technique failure. The difference in technique survival between PD and HD was more prominent in diabetic patients with a good nutritional status and in non-diabetic patients with a poor nutritional status.
Conclusions: In a prospective cohort of Korean patients with end-stage renal disease, PD was associated with a higher risk of technique failure than HD. Diabetic patients with a good nutritional status and non-diabetic patients with a poor nutritional status, as well as patients with a higher BMI, had an inferior technique survival rate with PD compared to HD.
키워드
Survival, Hemodialysis, Peritoneal dialysis, Body mass index, Diabetes
KMID :
0338420160310010106
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유효성결과(Recomendation)
The risk of technique failure was higher for peritoneal dialysis (PD) than hemodialysis; PD was associated with a higher risk of technique failure than HD.