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Duodenal adenocarcinoma following a neuroendocrine tumor in the duodenum

The Korean Journal of Internal Medicine 2014년 29권 1호 p.96 ~ p.100

(Kim Bun) - Yonsei University College of Medicine Department of Internal Medicine
허지혜(Huh Ji-Hye) - Yonsei University College of Medicine Department of Internal Medicine
김영숙(Kim Young-Sook) - Yonsei University College of Medicine Department of Internal Medicine
정문재(Chung Moon-Jae) - Yonsei University College of Medicine Department of Internal Medicine
박정엽(Park Jeong-Youp) - Yonsei University College of Medicine Department of Internal Medicine
송시영(Song Si-Young) - Yonsei University College of Medicine Department of Internal Medicine
박승우(Park Seung-Woo) - Yonsei University College of Medicine Department of Internal Medicine

Abstract

Primary duodenal adenocarcinoma is a rare malignant neoplasm accounting for 0.3% of all gastrointestinal tract carcinomas. We herein present one case of duodenal adenocarcinoma after duodenal neuroendocrine carcinoma. Poorly differentiated duodenal neuroendocrine carcinoma with liver metastasis (TxNxM1) was confirmed, and eight cycles of palliative chemotherapy (5-fluorouracil/etoposide/cisplatin) were administered. The patient was then in a clinically complete response status. About 1 year later, newly developed adenocarcinoma was detected at the same site. It was completely surgically resected, and the patient was cured.