ÀÌÈñ¿¬(Lee Hee-Yeon) - Catholic University College of Medicine Department of Internal Medicine
ÀÌÀ±Èñ(Lee Youn-Hee) - Catholic University College of Medicine St. Vincent¡¯s Hospital Department of Internal Medicine
±è¹ÎÁö(Kim Min-Ji) - Catholic University College of Medicine St. Vincent¡¯s Hospital Department of Internal Medicine
±èÈƱ³(Kim Hoon-Kyo) - Catholic University College of Medicine St. Vincent¡¯s Hospital Department of Internal Medicine
Abstract
Diarrhea is a common adverse event of docetaxel with 20%-40% of incidence and severe diarrhea occurs in 5%-6%. Several treatment guidelines for chemotherapy induced diarrhea (CID) exist, however the prophylaxis for that is not well known. We describe a new prophylactic approach for the CID with loperamide. A 72-yr-old male patient with stage IV non-small-cell lung cancer developed diarrhea repeatedly after docetaxel-cisplatin chemotherapy. His diarrhea persisted despite treatment including loperamide and fasting. However, the diarrhea was successfully prevented when loperamide was given before and after the chemotherapy. To our knowledge, this is the first report of prophylactic approach for the CID with loperamide.
Å°¿öµå
Docetaxel, Diarrhea, Loperamide
KMID :
0191120130280101549
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)
the diarrhea was successfully prevented when loperamide was given before and after the chemotherapy.