잠시만 기다려 주세요. 로딩중입니다.

말기 신질환 환자들에서 발생한 말초신경병증

Peripheral Neuropathy in Patients with End-Stage Renal Disease

대한근전도전기진단의학회지
2009년 11권 2호 p.55 ~ p.60
강석 ( Kang Seok ) - 고려대학교 의과대학 재활의학교실

권희규 ( Kwon Hee-Kyu ) - 고려대학교 의과대학 재활의학교실
편성범 ( Pyun Sung-Bom ) - 고려대학교 의과대학 재활의학교실
김규태 ( Kim Kyu-Tae ) - 고려대학교 의과대학 재활의학교실
이유나 ( Yi Yoo-Na ) - 고려대학교 의과대학 재활의학교실
윤형석 ( Yun Hyung-Seok ) - 고려대학교 의과대학 재활의학교실
부창수 ( Boo Chang-Su ) - 고려대학교 의과대학 내과학교실
조원용 ( Cho Won-Yong ) - 고려대학교 의과대학 내과학교실

Abstract

Objective: To investigate and analyze prevalence and characteristics of peripheral neuropathy in patients with end-stage renal disease (ESRD) according to the cause of ESRD.

Methods: Cross sectional study was conducted in 112 patients who had undergone hemodialysis (n= 64) or peritoneal dialysis (n= 48). The medical records were reviewed. Standard motor and sensory nerve conduction studies, F waves, and H reflexes were performed. Peripheral neuropathy (PN) was diagnosed and classified into 4 grades.

Results: PN was diagnosed in 58 patients (51.8%): 34 in hemodialysis (HD) group and 24 in peritoneal dialysis (PD) group. Forty two out of 47 patient with diabetes mellitus developed PN whereas 16 out of 65 did in non-diabetic patients (p<0.01). The severity of PN was as follows: Grade I, 12; Grade II, 11; Grade III, 26; Grade IV, 9. The duration of ESRD according to the severity of PN was not significant (p=0.056) in all the patients, but showed moderate correlation in non-diabetic patients (r=0.287, p<0.05).

Conclusion: The diabetic patients may develop severe degree of PN compared to those with other etiology of ESRD because the peripheral nerve could be affected from both diabetes mellitus and uremia.

키워드

원문 및 링크아웃 정보
등재저널 정보
학술진흥재단(KCI) 대한의학회 회원 
주제코드
주제명
(Target field)
연구대상
(Population)
연구참여
(Sample size)
대상성별
(Gender)
질병특성
(Condition Category)
연구환경
(Setting)
연구설계
(Study Design)
연구기간
(Period)
중재방법
(Intervention Type)
중재명칭
(Intervention Name)
키워드
(Keyword)
유효성결과
(Recomendation)
연구비지원
(Fund Source)
근거수준평가
(Evidence Hierarchy)
출판년도
(Year)
참여저자수
(Authors)
대표저자
(1st Authors)
Doi
KCD코드
ICD 03
건강보험코드