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폐쇄성 수면무호흡의 치료를 위한 이식형 치료기: 설하신경 자극 치료

An Implantable Device for Treatment of Obstructive Sleep Apnea: Hypoglossal Nerve Stimulation Therapy

대한이비인후과학회지-두경부외과학
2015년 58권 5호 p.299 ~ p.304
김상욱 ( Kim Sang-Wook ) - 경상대학교 의학전문대학원 이비인후과학교실

Abstract

Among current treatment options for obstructive sleep apnea (OSA) including surgeries and oral appliances, positive airway pressure (PAP) is accepted as a standard modality, particularly for moderate to severe OSA patients. Because long-term compliance for PAP is less than 50%, however, strong demands for a novel therapy have existed. Based on the findings that electromyographic activities of pharyngeal dilator muscles are significantly decreased in OSA patients during sleep, researches on hypoglossal nerve stimulation (HGNS) have been conducted. Therapeutic effects of HGNS on OSA have been proven through a series of clinical trials, and the American Food and Drug Administration recently approved its application on moderate to severe OSA patients who failed or are intolerant to PAP treatment. Given recent advances in HGNS therapy, it would be timely to review the history of HGNS and discuss its clinical implications.

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학술진흥재단(KCI) KoreaMed 대한의학회 회원 
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