잠시만 기다려 주세요. 로딩중입니다.

The Relation of Arterial Stiffness with Vascular Calcification and BMD in Chronic Kidney Disease

대한신장학회지
2009년 28권 5호 p.433 ~ p.443
신영신 ( Shin Young-Shin ) - 가톨릭대학교 의과대학 신장내과

신미정 ( Shin Mi-Jung ) - 가톨릭대학교 의과대학 신장내과
송호철 ( Song Ho-Cheol ) - 가톨릭대학교 의과대학 신장내과
김대범 ( Kim Dae-Bum ) - 가톨릭대학교 의과대학 신장내과
김영수 ( Kim Young-Soo ) - 가톨릭대학교 의과대학 신장내과
김병수 ( Kim Byung-Soo ) - 가톨릭대학교 의과대학 신장내과
김영옥 ( Kim Young-Ok ) - 가톨릭대학교 의과대학 신장내과
김용수 ( Kim Yong-Soo ) - 가톨릭대학교 의과대학 신장내과

Abstract

Purpose:Vascular calcification with arterial stiffness as well as bone mineral density was compared in hemodialysis, peritoneal dialysis patients, and pre-dialysis patients.

Methods:The calcification level of the aorta was scored, the arterial stiffness level was examined by pulse wave velocity (PWV), and bone mineral density was measured by the use of DEXA, and analyzed.

Results:PWV was significantly higher in the calcification group. The systolic blood pressure and the PWV value of the HD group was r=0.566 (p<0.001), the PD group was r=0.711 (p<0.001), and the pre-dialysis patients group was r=0.461 (p=0.001), and in all groups, a high correlation was shown. In the association of the PWV value with BMD and T score, in the PD patient group, with spine BMD, it was r=-0.351 (p<0.05), femur BMD was r=-0.510 (p<0.01), and femur T score was r=-0.527 (p= 0.001). In the multivariate analysis of the PWV value, in the HD group, age and systolic blood pressure were significant and in the PD group, calcification score femur BMD, femur T score, and CRP were significant factors. In the pre-dialysis patients group, only femur T score was detected to be a significant factor for PWV.

Conclusion:In hemodialysis patients, age and systolic blood pressure, and in peritoneal dialysis patients, vascular calcification and the BMD level were analyzed to be significant factors mediating effects on arterial stiffness.

키워드

원문 및 링크아웃 정보
등재저널 정보
학술진흥재단(KCI) KoreaMed 대한의학회 회원 
주제코드
주제명
(Target field)
연구대상
(Population)
연구참여
(Sample size)
대상성별
(Gender)
질병특성
(Condition Category)
연구환경
(Setting)
연구설계
(Study Design)
연구기간
(Period)
중재방법
(Intervention Type)
중재명칭
(Intervention Name)
키워드
(Keyword)
유효성결과
(Recomendation)
연구비지원
(Fund Source)
근거수준평가
(Evidence Hierarchy)
출판년도
(Year)
참여저자수
(Authors)
대표저자
(1st Authors)
Doi
KCD코드
ICD 03
건강보험코드