Hyun, Jihye; Ha, Moon Soo; Oh, Seung Young; Tae, Jong Hyun; Chi, Byung Hoon; Chang, In Ho; Kim, Tae-Hyoung; Myung, Soon Chul; Nguyen, Tuan Thanh; Kim, Jung Hoon; Kim, Jin Wook; Lee, Yong Seong; Lee, Jooyoung; Choi, Se Young
BMC cancer
2023May ; 23 ( 1 ) :395.
PMID : 37138203
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Hyun, Jihye - Department of Applied Statistics, Chung-Ang University, 84 Heukseok-Ro, Dongjak-Gu, 06974, Seoul, Republic of Korea.
Ha, Moon Soo - Department of Urology, Hyundae General Hospital, Chung-Ang University College of
Oh, Seung Young - Department of Urology, Hyundae General Hospital, Chung-Ang University College of
Tae, Jong Hyun - Department of Urology, Chung-Ang University Hospital, Chung-Ang University
Chi, Byung Hoon - Department of Urology, Chung-Ang University Hospital, Chung-Ang University
Chang, In Ho - Department of Urology, Chung-Ang University Hospital, Chung-Ang University
Kim, Tae-Hyoung - Department of Urology, Chung-Ang University Hospital, Chung-Ang University
Myung, Soon Chul - Department of Urology, Chung-Ang University Hospital, Chung-Ang University
Nguyen, Tuan Thanh - Department of Urology, Cho Ray Hospital, University of Medicine and Pharmacy, Ho
Kim, Jung Hoon - Department of Urology, Chung-Ang University Gwangmyeong Hospital, Chung-Ang
Kim, Jin Wook - Department of Urology, Chung-Ang University Gwangmyeong Hospital, Chung-Ang
Lee, Yong Seong - Department of Urology, Chung-Ang University Gwangmyeong Hospital, Chung-Ang
Lee, Jooyoung - Department of Applied Statistics, Chung-Ang University, 84 Heukseok-Ro,
Choi, Se Young - Department of Urology, Chung-Ang University Hospital, Chung-Ang University
ABSTRACT
BACKGROUND: We aimed to assess the trends in urinary tract infections (UTIs) and prognosis of patients with prostate cancer after radical prostatectomy (RP) and radiation therapy (RT) as definitive treatment options.
METHODS: The data of patients diagnosed with prostate cancer between 2007 and 2016 were collected from the National Health Insurance Service database. The incidence of UTIs was evaluated in patients treated with RT, open/laparoscopic RP, and robot-assisted RP. The proportional hazard assumption test was performed using the scaled Schoenfeld residuals based on a multivariable Cox proportional hazard model. Kaplan-Meier analysis were performed to assess survival.
RESULTS: A total of 28,887 patients were treated with definitive treatment. In the acute phase (?12?months), UTIs were more frequent in RT than in RP. In the early follow-up period, the risk of UTIs was higher in the open/laparoscopic RP group (aHR, 1.63; 95% CI, 1.44-1.83; p?
CONCLUSIONS: In patients treated with RP or RT, the incidence of UTIs was higher than that in the general population. RP posed a higher risk of UTIs than RT did in early follow-up period. Robot-assisted RP had a lower risk of UTIs than open/laparoscopic RP group in total period. UTI characteristics might be related to poor prognosis. CI - ¨Ï 2023. The Author(s).
keyword
Mortality; Prognosis; Radiation therapy; Radical prostatectomy; Risk factor; Urinary tract infection
MESH
Male, Humans, *Prostatic Neoplasms/epidemiology/radiotherapy/surgery, Prostatectomy/adverse effects, Prognosis, *Robotic Surgical Procedures/adverse effects, *Urinary Tract Infections/epidemiology/etiology/surgery, Retrospective Studies
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