Risk factor-based optimal endoscopic surveillance intervals after endoscopic submucosal dissection for gastric adenoma.

Noh, Choong-Kyun; Lee, Eunyoung; Lee, Gil Ho; Lim, Sun Gyo; Lee, Kee Myung; Roh, Jin; Kim, Young Bae; Park, Bumhee; Shin, Sung Jae
Scientific reports
2021Nov ; 11 ( 1 ) :21408.
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Noh, Choong-Kyun -
Lee, Eunyoung -
Lee, Gil Ho -
Lim, Sun Gyo -
Lee, Kee Myung -
Roh, Jin -
Kim, Young Bae -
Park, Bumhee -
Shin, Sung Jae -
ABSTRACT
To date, there exists no established endoscopic surveillance interval strategy after endoscopic submucosal dissection (ESD) for gastric adenoma. In this study, we suggest a risk factor-based statistical model for optimal surveillance intervals for gastric adenoma after ESD with curative resection. A cox proportional hazard model was applied to identify risk factors for recurrence after ESD. Patients (n?=?698) were categorized into groups based on the identified risk factors. The cumulative density of recurrence over time was computed using a cubic splined baseline hazard function, and the customized surveillance interval was modeled for each risk group. The overall cumulative incidence of recurrence was 7.3% (n?=?51). Risk factors associated with recurrence were male (hazard ratio [HR], 2.60, P?=?0.030), protruded scar (HR, 3.18, P?
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Surveillance intervals could be changed depending on risk factors instead of a uniform surveillance endoscopic interval for all patients.
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DOI
10.1038/s41598-021-00969-1
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ICD 03
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