Postoperative changes in left ventricular systolic function after combined mitral and aortic valve replacement in patients with rheumatic heart disease.

An, Sang-Mee; Nam, Jae-Sik; Kim, Ho Jin; Bae, Hyeun Joon; Chin, Ji-Hyun; Lee, Eun-Ho; Choi, In-Cheol
Journal of cardiac surgery
2021Oct ; 36 ( 10 ) :3654-3661.
저자 상세정보
An, Sang-Mee - Department of Anesthesiology and Pain Medicine, Ewha Womans University Seoul Hospital, Seoul, South Korea.
Nam, Jae-Sik - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Kim, Ho Jin - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Bae, Hyeun Joon - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Chin, Ji-Hyun - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Lee, Eun-Ho - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Choi, In-Cheol - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
ABSTRACT
BACKGROUNDS: We sought to identify short- and long-term changes in postoperative left ventricular systolic function in patients with rheumatic heart disease (RHD) who underwent combined aortic and mitral valve replacement.

METHODS: We analyzed 146 patients according to their preoperative left ventricular ejection fraction (LVEF) (113 with preoperative LVEF???0% and 33 with preoperative LVEF?<50%). A restricted cubic spline model was used to assess the effect of time on the postoperative changes in echocardiographic parameters.

RESULTS: There were no significant difference in preoperative and immediately postoperative LVEF before discharge in either group. During median follow-up of 3.2 years (interquartile range: 1.3-4.7 years) after surgery, postoperative LVEF increased slightly and then plateaued in patients with preoperative LVEF???0%, whereas it increased over 3-4 years after surgery and then gradually decreased in patients with preoperative LVEF?<50% (p?
keyword
double valve replacement; left ventricular ejection fraction; rheumatic heart disease
MESH
Aortic Valve/diagnostic imaging/surgery, *Heart Valve Prosthesis, *Heart Valve Prosthesis Implantation, Humans, Retrospective Studies, *Rheumatic Heart Disease/complications/surgery, Stroke Volume, *Ventricular Dysfunction, Left/diagnostic imaging, Ventricular Function, Left
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
Long-term postoperative LVEF showed a downward trend in RHD patients with reduced preoperative LVEF, whereas it reached a plateau in RHD patients with normal preoperative LVEF.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1111/jocs.15814
KCD코드
ICD 03
건강보험코드