Postoperative changes in left ventricular systolic function after combined mitral and aortic valve replacement in patients with rheumatic heart disease.

An, Sang-Mee; Nam, Jae-Sik; Kim, Ho Jin; Bae, Hyeun Joon; Chin, Ji-Hyun; Lee, Eun-Ho; Choi, In-Cheol
Journal of cardiac surgery
2021Oct ; 36 ( 10 ) :3654-3661.
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An, Sang-Mee - Department of Anesthesiology and Pain Medicine, Ewha Womans University Seoul Hospital, Seoul, South Korea.
Nam, Jae-Sik - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Kim, Ho Jin - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Bae, Hyeun Joon - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Chin, Ji-Hyun - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Lee, Eun-Ho - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Choi, In-Cheol - Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
ABSTRACT
BACKGROUNDS: We sought to identify short- and long-term changes in postoperative left ventricular systolic function in patients with rheumatic heart disease (RHD) who underwent combined aortic and mitral valve replacement.

METHODS: We analyzed 146 patients according to their preoperative left ventricular ejection fraction (LVEF) (113 with preoperative LVEF???0% and 33 with preoperative LVEF?<50%). A restricted cubic spline model was used to assess the effect of time on the postoperative changes in echocardiographic parameters.

RESULTS: There were no significant difference in preoperative and immediately postoperative LVEF before discharge in either group. During median follow-up of 3.2 years (interquartile range: 1.3-4.7 years) after surgery, postoperative LVEF increased slightly and then plateaued in patients with preoperative LVEF???0%, whereas it increased over 3-4 years after surgery and then gradually decreased in patients with preoperative LVEF?<50% (p?
keyword
double valve replacement; left ventricular ejection fraction; rheumatic heart disease
MESH
Aortic Valve/diagnostic imaging/surgery, *Heart Valve Prosthesis, *Heart Valve Prosthesis Implantation, Humans, Retrospective Studies, *Rheumatic Heart Disease/complications/surgery, Stroke Volume, *Ventricular Dysfunction, Left/diagnostic imaging, Ventricular Function, Left
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Long-term postoperative LVEF showed a downward trend in RHD patients with reduced preoperative LVEF, whereas it reached a plateau in RHD patients with normal preoperative LVEF.
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DOI
10.1111/jocs.15814
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ICD 03
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