Hwang, You Mi; Kim, Jun; Nam, Gi Byoung; Choi, Kee Joon; Park, Duk-Woo; Kang, Do-Yoon; Park, Seung-Jung; Park, Seo Young
Medicine
2021Jun ; 100 ( 22 ) :e26123.
PMID : 34087862
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Hwang, You Mi - Department of Cardiology, St. Vincent's Hospital, The Catholic University of Korea.
Kim, Jun - Department of Cardiology.
Nam, Gi Byoung - Department of Cardiology.
Choi, Kee Joon - Department of Cardiology.
Park, Duk-Woo - Department of Cardiology.
Kang, Do-Yoon - Department of Cardiology.
Park, Seung-Jung - Department of Cardiology.
Park, Seo Young - Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
ABSTRACT
Transcatheter aortic valve replacement (TAVR) is a standard treatment indicated for severe aortic stenosis in high-risk patients. The objective of this study was to evaluate the incidence of pacemaker dependency after permanent pacemaker implantation (PPI) following TAVR or surgical aortic valve replacement (SAVR) and the risk of mortality at a tertiary center in Korea.In this retrospective study conducted at a single tertiary center, clinical outcomes related to pacemaker dependency were evaluated for patients implanted with pacemakers after TAVR from January 2012 to November 2018 and post-SAVR from January 2005 to May 2015. Investigators reviewed patients' electrocardiograms and baseline rhythms as well as conduction abnormalities. Pacemaker dependency was defined as a ventricular pacing rate > 90% with an intrinsic rate of <40?bpm during interrogation.Of 511 patients who underwent TAVR for severe AS, 37(7.3%) underwent PPI after a median duration of 6 (3-7) days, whereas pacemakers were implanted after a median interval of 13 (8-28) days post-SAVR in 10 of 663 patients (P?.001). Pacemaker dependency was observed in 36 (97.3%) patients during 7?days immediately post-TAVR and in 25 (64.9%) patients between 8 and 180?days post-TAVR. Pacemaker dependency occurred after 180?days in 17 (50%) patients with TAVR and in 4 (44.4%) patients with SAVR. Twelve (41.4%) patients were pacemaker-dependent after 365?days post-TAVR.Pacemaker dependency did not differ at 6?months after TAVR vs SAVR. In patients undergoing post-TAVR PPI, 58.6% were not pacemaker-dependent at 1 year after the TAVR procedure. CI - Copyright ??2021 the Author(s). Published by Wolters Kluwer Health, Inc.
keyword
aortic valve stenosis; artificial; heart conduction system; pacemaker; transcatheter aortic valve replacement
MESH
Aged, Aged, 80 and over, Aortic Valve Stenosis/*surgery, Electrocardiography, Female, Humans, Male, Middle Aged, Pacemaker, Artificial/*statistics & numerical data, Republic of Korea, Retrospective Studies, Tertiary Care Centers, Transcatheter Aortic Valve Replacement/*statistics & numerical data
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