KCTBASE

Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy

Lee, Dong Sup; Lee, Seung-Ju

Scientific reports
2021Feb ; 11 ( 1 ) :3632.

PMID : 33574414

저자 상세정보

Lee, Dong Sup - Department of Urology, St. Vincent's Hospital, The Catholic University of Korea, College of Medicine, 93-6 Ji-dong Paldal-gu, Suwon, 16247, Korea.
Lee, Seung-Ju - Department of Urology, St. Vincent's Hospital, The Catholic University of Korea,

ABSTRACT

Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated. Further evaluation of urodynamic parameters according to changes in symptoms was made. Although change in bladder compliance was correlated with changes in OAB symptoms, not the relative change of bladder compliance but the relative change in the MUCP was reliable factor when OAB symptoms were deteriorated. In general, prostatectomy did not deteriorate the condition of the detrusor; rather, change in the MUCP could be responsible for postprostatectomy OAB.

keyword

MESH

링크

PubMed

주제코드

주제명(Target field)

연구대상(Population)

연구참여(Sample size)

대상성별(Gender)

질병특성(Condition Category)

연구환경(Setting)

연구설계(Study Design)

연구기간(Period)

중재방법(Intervention Type)

중재명칭(Intervention Name)

키워드(Keyword)

유효성결과(Recomendation)

In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated; robotic radical prostatectomy did not deteriorate the detrusor’s condition, including compliance and/or IDC. In cases of OAB symptom deterioration, the MUCP may exert a central role among urodynamic parameters.

연구비지원(Fund Source)

근거수준평가(Evidence Hierarchy)

출판년도(Year)

참여저자수(Authors)

대표저자

DOI

10.1038/s41598-021-83143-x

KCD코드

ICD 03

건강보험코드