Hwang, In Cheol; Park, Young Min; Kang, Woong Chol; Moon, Jeonggeun
Cardiology
2020Sep ; 15 ( 9 ) :1-4.
PMID : 32911470
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Hwang, In Cheol - Department of Family Medicine, Gachon University College of Medicine, Incheon, Republic of Korea.
Park, Young Min - Department of Family Medicine, National Health Insurance Corporation Ilsan Hospital,
Kang, Woong Chol - Cardiology Division, Department of Internal Medicine, Gachon University College of
Moon, Jeonggeun - Cardiology Division, Department of Internal Medicine, Gachon University College of
ABSTRACT
BACKGROUND: The association between height and cardiovascular disease (CVD) has been reported in epidemiological studies for decades; however, the mechanism for this relationship is still unclear. We previously reported that dyslipidemia was associated with adult height in Korean men without CVD. OBJECTIVES: This study explored the potential -relationship between height and dyslipidemia in premenopausal women.
METHODS: This study used data from the 2007-2016 Korea National Health and Nutritional Examination Survey (KNHANES). We identified 16,361 premenopausal women aged ??9 years without a history of CVD (myocardial infarction/stroke) or cancer. Fasting total cholesterol, triglyceride, and high-density lipoprotein cholesterol (HDL-C) levels were measured. Dyslipidemia was further classified as hypercholesterolemia (total cholesterol level ??40 mg/dL or treatment with lipid-lowering medications), hypertriglyceridemia (triglyceride level ??00 mg/dL), and low HDL-C (HDL-C level <40 mg/dL). Subjects were divided into four groups by their height (<155, 155-159.9, 160-164.9, and ??65 cm), and the prevalence of dyslipidemia was compared.
RESULTS: Multiple regression analysis revealed that short premenopausal women had a higher likelihood of hypercholesterolemia (ptrend = 0.002), hypertriglyceridemia (ptrend = 0.010), and low HDL-C (ptrend = 0.002) when adjusted for age, comorbidities, waist circumference, health-related habits, and economic status. CONCLUSION: There was a dose-dependent correlation between adult height and adverse lipid profile in premenopausal Korean women who did not have CVD. This finding could serve as further evidence that dyslipidemia can be a link between shortness and CVD. CI - ??2020 S. Karger AG, Basel.
keyword
Dyslipidemia; Epidemiology; Height; Risk factor; Women
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