Lee, Ji Yeon; Hong, Seung Wan; Hyun, Miri; Park, Jae Seok; Lee, Jae Hyuck; Suh, Young Sung; Kim, Dae Hyun; Han, Seong-Wook; Cho, Chi-Heum; Kim, Hyun Ah
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2020Sep ; 98 ( 3 ) :462-466.
PMID : 32702415
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Lee, Ji Yeon - Department of Infectious Disease, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.
Hong, Seung Wan - Department of Family Medicine, Keimyung University Dongsan Hospital, Keimyung
Hyun, Miri - Department of Infectious Disease, Keimyung University Dongsan Hospital, Keimyung
Park, Jae Seok - Department of Pulmonology, Keimyung University Dongsan Hospital, Keimyung University
Lee, Jae Hyuck - Department of Family Medicine, Daegu Dongsan Hospital, Daegu, Republic of Korea.
Suh, Young Sung - Department of Family Medicine, Keimyung University Dongsan Hospital, Keimyung
Kim, Dae Hyun - Department of Family Medicine, Keimyung University Dongsan Hospital, Keimyung
Han, Seong-Wook - Department of Cardiology, Keimyung University Dongsan Hospital, Keimyung University
Cho, Chi-Heum - Department of Obstetrics and Gynecology, Keimyung University Dongsan Hospital,
Kim, Hyun Ah - Department of Infectious Disease, Keimyung University Dongsan Hospital, Keimyung
ABSTRACT
OBJECTIVES: Two Coronavirus Disease 2019 (COVID-19) outbreaks simultaneously occurred at a church and a long-term care facility in Daegu, South Korea. This study aimed to investigate the epidemiological characteristics of COVID-19 and factors related to severe outcomes.
METHODS: We enrolled all inpatients diagnosed with COVID-19 between February 21 and April 2, 2020, in Daegu Dongsan Hospital. We analyzed their clinical and demographic data, laboratory parameters, radiological findings, symptoms, and treatment outcomes.
RESULTS: Of 694 patients, severe cases accounted for 19.7% (137 patients). No severe case was observed among patients aged ??9 years. Hypertension was the most common comorbidity (27%), and cough was the most common symptom (59%). Asymptomatic patients accounted for 14.4% of cases. Lymphopenia, lactate dehydrogenase, C-reactive protein, and albumin were associated with severe outcomes. The first outbreak was mostly associated with younger age groups, and asymptomatic patients mostly showed mild progression. In the second outbreak involving a long-term care facility, both the number of severe patients and the mortality rate were higher.
CONCLUSIONS: The overall mortality in Daegu was low, which might have resulted from large scale mass screening to detect patients and starting appropriate treatment, including hospitalization for severe cases, and quarantine for asymptomatic patients. CI - Copyright ??2020 The Authors. Published by Elsevier Ltd.. All rights reserved.
keyword
Coronavirus Disease 2019 (COVID-19); Epidemiology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
MESH
Adolescent, Adult, Aged, Aged, 80 and over, Betacoronavirus/genetics/*physiology, C-Reactive Protein/metabolism, Child, Child, Preschool, Coronavirus Infections/*diagnosis/*epidemiology/metabolism/virology, Cough, Disease Outbreaks, Female, Hospitals, Humans, Male, Mass Screening, Middle Aged, Pandemics, Pneumonia, Viral/*diagnosis/*epidemiology/metabolism/virology, Republic of Korea/epidemiology, Treatment Outcome, Young Adult
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