Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation.

Lee, Min Kyoung; Baek, Jung Hwan; Chung, Sae Rom; Choi, Young Jun; Lee, Yu-Mi; Kim, Tae Yong; Lee, Jeong Hyun
Endocrinology and metabolism (Seoul, Korea)
2020Jun ; 35 ( 2 ) :407-415.
저자 상세정보
Lee, Min Kyoung -
Baek, Jung Hwan -
Chung, Sae Rom -
Choi, Young Jun -
Lee, Yu-Mi -
Kim, Tae Yong -
Lee, Jeong Hyun -
BACKGROUND: Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose in water (5% DW) can reduce nerve damage during RFA. This study validated the efficacy of injecting cold 5% DW for management of nerve damage during RFA.

METHODS: Between November 2017 and December 2018, 242 patients underwent 291 RFA sessions for treatment of benign thyroid nodules or recurrent thyroid cancers. Using a standardized technique, cold (0°C to 4°C) 5% DW was immediately injected around the damaged nerve into patients with any symptoms suggesting nerve damage. The incidence of nerve damage, the volume of 5% DW injected, symptom recovery time and the incidence of permanent nerve damage were evaluated.

RESULTS: Nineteen patients experienced nerve damage symptoms related to 21 RFA sessions, including 17 patients during 19 sessions and two patients on the day after two sessions. Patients with nerve damage symptoms detected during RFA were treated by injection of a mean 41 mL (range, 3 to 260) cold 5% DW, but the two patients who experienced symptoms the next day did not receive cold 5% DW injections. Immediate recovery was observed after 15 RFA sessions in 14 patients. No patient experienced permanent nerve damage. CONCLUSION: Injection of cold 5% DW is effective in managing nerve damage during RFA of thyroid lesions.
Radiofrequency ablation; Ultrasonography; Thyroid nodule

주제명(Target field)
연구참여(Sample size)
질병특성(Condition Category)
연구설계(Study Design)
중재방법(Intervention Type)
중재명칭(Intervention Name)
Injection of cold 5% DW is effective in managing nerve damage during RFA of thyroid lesions.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
ICD 03