Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea.

Ahn, Jin Young; Sohn, Yujin; Lee, Su Hwan; Cho, Yunsuk; Hyun, Jong Hoon; Baek, Yae Jee; Jeong, Su Jin; Kim, Jung Ho; Ku, Nam Su; Yeom, Joon Sup; Roh, Juhye; Ahn, Mi Young; Chin, Bum Sik; Kim, Young Sam; Lee, Hyukmin; Yong, Dongeun; Kim, Hyun Ok; Kim, Sinyoung; Choi, Jun Yong
Journal of Korean medical science
2020Apr ; 35 ( 14 ) :e149.
ÀúÀÚ »ó¼¼Á¤º¸
Ahn, Jin Young - Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Sohn, Yujin - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Lee, Su Hwan - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Cho, Yunsuk - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Hyun, Jong Hoon - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Baek, Yae Jee - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Jeong, Su Jin - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Kim, Jung Ho - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Ku, Nam Su - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Yeom, Joon Sup - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Roh, Juhye - Department of Laboratory Medicine, Severance Hospital, Yonsei University College
Ahn, Mi Young - Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.
Chin, Bum Sik - Department of Internal Medicine, National Medical Center, Seoul, Korea.
Kim, Young Sam - Department of Internal Medicine, Severance Hospital, Yonsei University College of
Lee, Hyukmin - Department of Laboratory Medicine, Severance Hospital, Yonsei University College
Yong, Dongeun - Department of Laboratory Medicine, Severance Hospital, Yonsei University College
Kim, Hyun Ok - Department of Laboratory Medicine, Severance Hospital, Yonsei University College
Kim, Sinyoung - Department of Laboratory Medicine, Severance Hospital, Yonsei University College
Choi, Jun Yong - Department of Internal Medicine, Severance Hospital, Yonsei University College of
ABSTRACT
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma has been expected to increase survival rates as in the case with other emerging viral infections. We describe two cases of COVID-19 treated with convalescent plasma infusion. Both patients presented severe pneumonia with acute respiratory distress syndrome and showed a favorable outcome after the use of convalescent plasma in addition to systemic corticosteroid. To our knowledge, this is the first report of the use of convalescent plasma therapy for COVID-19 in Korea. CI - (c) 2020 The Korean Academy of Medical Sciences.
keyword
COVID-19; Convalescent Plasma; Coronavirus; SARS-CoV-2; Treatment
MESH
Aged, *Betacoronavirus, Coronavirus Infections/*therapy, Female, Humans, Immunization, Passive, Male, Pandemics, Pneumonia, Viral/*therapy, Republic of Korea, Respiratory Distress Syndrome, Adult/therapy
¸µÅ©

ÁÖÁ¦ÄÚµå
ÁÖÁ¦¸í(Target field)
¿¬±¸´ë»ó(Population)
¿¬±¸Âü¿©(Sample size)
´ë»ó¼ºº°(Gender)
Áúº´Æ¯¼º(Condition Category)
¿¬±¸È¯°æ(Setting)
¿¬±¸¼³°è(Study Design)
¿¬±¸±â°£(Period)
ÁßÀç¹æ¹ý(Intervention Type)
ÁßÀç¸íĪ(Intervention Name)
Å°¿öµå(Keyword)
À¯È¿¼º°á°ú(Recomendation)
Convalescent plasma from patients who have recovered from COVID-19 infection might be an additional option to treat patients without causing any severe adverse effects.
¿¬±¸ºñÁö¿ø(Fund Source)
±Ù°Å¼öÁØÆò°¡(Evidence Hierarchy)
ÃâÆdz⵵(Year)
Âü¿©ÀúÀÚ¼ö(Authors)
´ëÇ¥ÀúÀÚ
DOI
10.3346/jkms.2020.35.e149
KCDÄÚµå
ICD 03
°Ç°­º¸ÇèÄÚµå